Evidence map›Paper›PMID 36484353›Full record

ArticleMolecular medicine reports2023

Significance of placental CD200 expression in patients with preeclampsia: Comparison between early‑ and late‑onset patients.

Hiroaki Tsubokura, Mitsuaki Ishida, Akemi Nishigaki, Takuya Yokoe, Shinnosuke Komiya, Yusuke Butsuhara, Aya Yoshida, Yoji Hisamatsu, Yoshiko Hashimoto, Tomoko Tsuzuki-Nakao and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hiroaki TsubokuraDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Mitsuaki IshidaDepartment of Pathology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka 569‑8686, Japan.
Akemi NishigakiDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Takuya YokoeDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Shinnosuke KomiyaDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Yusuke ButsuharaDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Aya YoshidaDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Yoji HisamatsuDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Yoshiko HashimotoDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Tomoko Tsuzuki-NakaoDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Hiromi MurataDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Koji TsutaDepartment of Pathology and Division of Diagnostic Pathology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Hidetaka OkadaDepartment of Obstetrics and Gynecology, Kansai Medical University, Hirakata, Osaka 573‑1191, Japan.
Kansai Medical University · JPOsaka University of Pharmaceutical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia, characterized by high blood pressure and proteinuria during pregnancy, causes serious complications in both the mother and the fetus. Although there have been several studies on the causes of preeclampsia, the detailed mechanism of this disease remains unclear. Moreover, a few reports have focused on the causes of preeclampsia in number of weeks at onset. The present study aimed to elucidate the differences between early‑ and late‑onset preeclampsia. This study enrolled patients with preeclampsia from January 2014 to December 2020. They were classified into early‑ (<34 weeks) and late‑onset (≥34 weeks) preeclampsia groups. The expression profiles of 770 immune‑related genes were studied in the placental tissue from five patients each in the early‑ and late‑onset groups. The expression of CD200 in the trophoblasts of the placenta of 26 and 27 patients in early‑ and late‑onset groups, respectively, was also analyzed using immunostaining. Analysis of extracted RNA indicated that

Indexed as

PlacentaFemaleHumansPregnancyCD200early‑onsetlate‑onsetplacentapreeclampsia

Identifiers

PMID36484353
PMCPMC9743378
OpenAlexW4310685596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.