Evidence map›Paper›PMID 36484064›Full record

Trial reportTransplant international : official journal of the European Society for Organ Transplantation2022

Autologous Mesenchymal Stem Cells for Treatment of Chronic Active Antibody-Mediated Kidney Graft Rejection: Report of the Phase I/II Clinical Trial Case Series.

Željka Večerić-Haler, Matjaž Sever, Nika Kojc, Philip F Halloran, Emanuela Boštjančič, Gregor Mlinšek, Manca Oblak, Primož Poženel, Urban Švajger, Katrina Hartman and 7 more

Open access · goldAbstract readClinical Trial, Phase IIClinical Trial, Phase I
In one paragraph

Trial report in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. The Landscape of Advanced Therapy Medicinal Products in Slovenian Transfusion Medicine: A Review of Past and Future Outlook.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Željka Večerić-HalerDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Matjaž SeverDepartment of Haematology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Nika KojcInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Philip F HalloranDivision of Nephrology and Transplant Immunology, Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada.
Emanuela BoštjančičInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Gregor MlinšekDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Manca OblakDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Primož PoženelDivision for Cells and Tissue, Blood Transfusion Centre of Slovenia, Ljubljana, Slovenia.
Urban ŠvajgerDivision for Cells and Tissue, Blood Transfusion Centre of Slovenia, Ljubljana, Slovenia.
Katrina HartmanDivision for Cells and Tissue, Blood Transfusion Centre of Slovenia, Ljubljana, Slovenia.
Miomir KneževičEducell d.o.o Cell Therapy Service, Ljubljana, Slovenia.
Ariana BarličEducell d.o.o Cell Therapy Service, Ljubljana, Slovenia.
Lenart GirandonEducell d.o.o Cell Therapy Service, Ljubljana, Slovenia.
Andreja Aleš RiglerDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Samo ZverDepartment of Haematology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Jadranka Buturović PonikvarDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Miha ArnolDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
University of Ljubljana · SIBlood Transfusion Centre of Slovenia · SILjubljana University Medical Centre · SIB2 (Slovenia) · SIEducell · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cell (MSCs) therapy has already been studied in kidney transplant recipients (KTRs), and the available data showed that it is safe and well tolerated. The aim of this study was to evaluate the safety and efficacy of autologous MSCs in combination with standard therapy in KTRs with biopsy-proven chronic active antibody-mediated rejection (AMR). Patients with biopsy-proven chronic active AMR received treatment with autologous bone marrow-derived MSCs (3 × 10

Indexed as

Graft RejectionMesenchymal Stem CellsHumansKidneyantibody mediated rejectionkidney allograftkidney transplantmesenchymal stem cellsstem cells

Identifiers

PMID36484064
PMCPMC9722440
OpenAlexW4309524066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.