Evidence map›Paper›PMID 36483900›Full record

ArticleCureus2022

Preeclampsia Incidence and Its Maternal and Neonatal Outcomes With Associated Risk Factors.

Bisma Khan, Razia Allah Yar, Ayesha Khan Khakwani, Sajilah Karim, Hafiz Arslan Ali

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Sedentary behavior during pregnancy and risk of pre-eclampsia and/or gestational hypertension: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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  16. Comparison of first trimester preeclampsia combined screening performances with various approaches in the Indonesian population.Journal of perinatology : official journal of the California Perinatal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bisma KhanDepartment of Zoology, University of Central Punjab, Lahore, PAK.
Razia Allah YarDepartment of Zoology, University of Central Punjab, Lahore, PAK.
Ayesha Khan KhakwaniObstetrics and Gynecology, Nishtar Hospital, Multan, PAK.
Sajilah KarimObstetrics and Gynecology, Nishtar Hospital, Multan, PAK.
Hafiz Arslan AliDepartment of Zoology, University of Central Punjab, Lahore, PAK.
University of Central Punjab · PKNishtar Medical College and Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective Preeclampsia is a hypertensive disorder that usually arises after 20 weeks of pregnancy. It is considered a major cause of maternal and fetal mortality worldwide. High blood pressure and high proteinuria are the two main characteristics of preeclamptic patients. Preeclampsia leads to either severe or mild conditions, but in both cases, it affects the organs of the mother and fetus. This study was conducted to determine the prevalence of preeclampsia and associated risk factors (family history, age, hypertension, and diabetes) and to investigate its fetal and maternal outcomes. Methodology This prospective study was conducted at three healthcare units in the Multan district and involved patients with gestational hypertension. Patients were diagnosed on the basis of blood pressure values, urine tests, and through Doppler ultrasound. Further investigations were conducted, including a complete hemogram and a 24-hour test for proteinuria. Results for preeclampsia-related maternal and perinatal outcomes were documented and statistical analysis was performed to analyze the data. Results A total of 142 patients were diagnosed with gestational hypertension and preeclampsia during the two-year study period. Our findings showed 8.67% cases of gestational hypertension and 3% of preeclampsia. The majority of the preeclamptic patients were less than 24 years of age (33.3%), belonged to lower socioeconomic classes (44.4%), and had low educational levels (81.1%). A close association of family history (36.67%) with diabetes (15.5%) and chronic hypertension (5.55%) was observed in these patients. Maternal and fetal outcomes were related to maternal blood pressure. A significant incidence of premature births (45.6%) and a majority of cesarean cases (63.4%) with severe complications were observed. Data from preeclamptic patients showed high albuminuria levels (42.2%) with problems like renal infection, pulmonary edema, and severe anemia. During the study period, a neonatal death rate of 11.1% was observed as well as issues like respiratory tract syndrome, asphyxia, and growth retardation. Conclusion This study showed that poor economic and educational levels are significantly associated with this disease. A high rate of maternal and neonatal morbidity with neonatal mortality was investigated. Mild to severe outcomes were observed in the form of cesarean deliveries and preterm births. Serious complications lead to ICU admissions causing a serious burden on healthcare units. Paying more attention to the healthcare needs of pregnant women helps to identify preeclampsia earlier and also minimizes the complications associated with it.

Indexed as

arrhythmiafetal morbidityhypertensionmaternal and fetal outcomespreeclampsiaproteinuria

Identifiers

PMID36483900
PMCPMC9723483
OpenAlexW4308275209

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.