Evidence map›Paper›PMID 36483605›Full record

ArticleWorld journal of hepatology2022

Liver test abnormalities in asymptomatic and mild COVID-19 patients and their association with viral shedding time.

Si-Yi Yu, Jia-Rong Xie, Jun-Jun Luo, Hong-Peng Lu, Lei Xu, Jun-Jie Wang, Xue-Qin Chen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Si-Yi YuDepartment of Gastroenterology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Jia-Rong XieDepartment of Gastroenterology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Jun-Jun LuoDepartment of Cardiology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Hong-Peng LuDepartment of Gastroenterology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Lei XuDepartment of Gastroenterology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Jun-Jie WangDepartment of Information Technology, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China.
Xue-Qin ChenDepartment of Traditional Medicine, Ningbo First Hospital, Ningbo 315010, Zhejiang Province, China. cxq2316@163.com.
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsymptomatic infections and mild symptoms are common in patients infected with the Omicron variant, and data on liver test abnormalities are rare.

aimTo evaluated the clinical characteristics of asymptomatic and mild coronavirus disease 2019 (COVID-19) patients with abnormal liver test results.

methodsThis retrospective study included 661 laboratory-confirmed asymptomatic and mild COVID-19 patients who were treated in two makeshift hospitals in Ningbo from April 5, 2022 to April 29, 2022. Clinical information and viral shedding time were collected, and univariate and multivariate logistic regression models were performed in statistical analyses.

resultsOf the 661 patients, 83 (12.6%) had liver test abnormalities, and 6 (0.9%) had liver injuries. Abnormal liver tests revealed a reliable correlation with a history of liver disease (

conclusionObesity and a history of liver disease are risk factors for liver test abnormalities. Being male and an older age are potential risk factors. Attention should be given to liver tests in asymptomatic and mild COVID-19 patients, which has crucial clinical significance for evaluating the viral shedding time.

Indexed as

Asymptomatic carriersCOVID-19Liver test abnormalitiesMild casesRisk factorsViral shedding time

Identifiers

PMID36483605
PMCPMC9724107
OpenAlexW4310338870

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.