Evidence map›Paper›PMID 36483536›Full record

ArticleFrontiers in molecular biosciences2022

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties.

Alessandro Vacchini, Elisa Maffioli, Dario Di Silvestre, Cinzia Cancellieri, Samantha Milanesi, Simona Nonnis, Sabrina Badanai, Pierluigi Mauri, Armando Negri, Massimo Locati and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Alessandro VacchiniIRCCS Humanitas Research Hospital, Milan, Italy.
Elisa MaffioliDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.
Dario Di SilvestreInstitute of Technologies in Biomedicine, National Research Council (ITB-CNR), Milan, Italy.
Cinzia CancellieriIRCCS Humanitas Research Hospital, Milan, Italy.
Samantha MilanesiIRCCS Humanitas Research Hospital, Milan, Italy.
Simona NonnisDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.
Sabrina BadanaiIRCCS Humanitas Research Hospital, Milan, Italy.
Pierluigi MauriCIMAINA, Milan, Italy.
Armando NegriDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.
Massimo LocatiIRCCS Humanitas Research Hospital, Milan, Italy.
Gabriella TedeschiDepartment of Veterinary Medicine and Animal Science, University of Milan, Lodi, Italy.
Elena Monica BorroniIRCCS Humanitas Research Hospital, Milan, Italy.
University of Milan · ITIRCCS Humanitas Research Hospital · ITCIMA Research Foundation · ITNational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ACKR2 is an atypical chemokine receptor which is structurally uncoupled from G proteins and is unable to activate signaling pathways used by conventional chemokine receptors to promote cell migration. Nonetheless, ACKR2 regulates inflammatory and immune responses by shaping chemokine gradients in tissues

Indexed as

ACKR2CCR5phosphoproteomesignalingSILAC

Identifiers

PMID36483536
PMCPMC9723398
OpenAlexW4309718270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.