Evidence map›Paper›PMID 36483473›Full record

ArticleFrontiers in pediatrics2022

The longitudinal course of pediatric acute respiratory distress syndrome and its time to resolution: A prospective observational study.

Judith Ju Ming Wong, Herng Lee Tan, Rehena Sultana, Yi-Jyun Ma, Apollo Aguilan, Siew Wah Lee, Pavanish Kumar, Yee Hui Mok, Jan Hau Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Author Response: A Neurological Outcome Score for Ventilated PICU Patients Should Only Include Neurological, Objective Outcome Parameters.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Judith Ju Ming WongChildren's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
Herng Lee TanChildren's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
Rehena SultanaCenter for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Yi-Jyun MaDuke-NUS Medical School, Singapore, Singapore.
Apollo AguilanChildren's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
Siew Wah LeePediatric Intensive Care Unit, Hospital Tengku Ampuan Rahimah, Selangor, Malaysia.
Pavanish KumarTranslational Immunology Institute, SingHealth/Duke-NUS Academic Medical Centre, Singapore, Singapore.
Yee Hui MokChildren's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
Jan Hau LeeChildren's Intensive Care Unit, Department of Pediatric Subspecialties, KK Women's and Children's Hospital, Singapore, Singapore.
KK Women's and Children's Hospital · SGDuke-NUS Medical School · SGSingHealth Duke-NUS Academic Medical Centre · SGTengku Ampuan Rahimah Hospital · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The longitudinal course of patients with pediatric acute respiratory distress syndrome (PARDS) is not well described. In this study, we describe the oxygenation index (OI) and oxygen saturation index (OSI) in mild, moderate, and severe PARDS over 28 days and provide pilot data for the time to resolution of PARDS ( Methods: This prospective observational study recruited consecutive patients with PARDS. OI and OSI were trended daily over 28 days. Results: There were 121 children included in this study, 33/121(27.3%), 44/121(36.4%), and 44/121(36.4%) in the mild, moderate, and severe groups of PARDS, respectively. OI and OSI clearly differentiated mild, moderate, and severe groups in the first 7days of PARDS; however, this differentiation was no longer present after 7days. Median Conclusion: The oxygenation defect in PARDS took progressively longer to resolve across the mild, moderate, and severe groups.

Indexed as

acute lung injuryacute respiratory distress syndromeartificial respirationcritical care outcomesnon-invasive ventilationoxygen inhalation therapypediatric intensive care unit

Identifiers

PMID36483473
PMCPMC9723458
OpenAlexW4309711140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.