Evidence map›Paper›PMID 36483314›Full record

ArticleWellcome open research2022

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.

Thomas W M Crozier, Edward J D Greenwood, James C Williamson, Wenrui Guo, Linsey M Porter, Ildar Gabaev, Ana Teixeira-Silva, Guinevere L Grice, Arthur Wickenhagen, Richard J Stanton and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Thomas W M Crozier *Department of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID https://orcid.org/0000-0003-0951-4588
Edward J D Greenwood *Department of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID https://orcid.org/0000-0002-5224-0263
James C Williamson *Department of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.
Wenrui GuoDepartment of Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.
Linsey M PorterDepartment of Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.
Ildar GabaevDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.
Ana Teixeira-SilvaDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID https://orcid.org/0000-0002-9011-9501
Guinevere L GriceDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.
Arthur WickenhagenMRC - University of Glasgow Centre for Virus Research, Glasgow, G61 1QH, UK.ORCID https://orcid.org/0000-0001-5470-1505
Richard J StantonDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.ORCID https://orcid.org/0000-0002-6799-1182
Eddie C Y WangDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.ORCID https://orcid.org/0000-0002-2243-4964
Sam J WilsonMRC - University of Glasgow Centre for Virus Research, Glasgow, G61 1QH, UK.
Nicholas J MathesonDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.
James A NathanDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID https://orcid.org/0000-0002-0248-1632
Frank McCaughanDepartment of Medicine, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.
Paul J LehnerDepartment of Medicine, Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, CB2 0AW, UK.
University of Cambridge · GBCardiff University · GBMRC University of Glasgow Centre for Virus Research · GBNHS Blood and Transplant · GB

Funding

Medical Research Council MC_PC_19026Medical Research Council MR/P001602/1Medical Research Council MR/S00971X/1Medical Research Council MR/T032413/1Medical Research Council MR/V000489/1Medical Research Council MR/V011561/1Medical Research Council MR/V028448/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/S001204/1Wellcome Trust 210688/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CoronavirusCOVID-19proteomicsSARS-CoV-2

Identifiers

PMID36483314
PMCPMC9706147
OpenAlexW4295599288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.