Evidence map›Paper›PMID 36483204›Full record

ArticleFrontiers in microbiology2022

The combination effect of meropenem/sulbactam/polymyxin-B on the pharmacodynamic parameters for mutant selection windows against carbapenem-resistant

Jiayuan Zhang, Shuo Diao, Yanfei Liu, Hongxiang Wang, Yuwei Liu, Shixing Zhu, Kun Feng, Xiaoqian Tang, Charles Oo, Peijuan Zhu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Jiayuan ZhangSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Shuo DiaoSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Yanfei LiuDepartment of Laboratory Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hongxiang WangLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.
Yuwei LiuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Shixing ZhuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Kun FengSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Xiaoqian TangLaboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, Qingdao, China.
Charles OoSunLife Biopharma, Morris Plains, NJ, United States.
Peijuan ZhuDepartment of Pharmacology, University of Pennsylvania, Philadelphia, PA, United States.
Zhihua LvSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Mingming YuSchool of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
Sherwin K B SyDepartment of Statistics, State University of Maringá, Maringá, Brazil.
Yuanqi ZhuDepartment of Laboratory Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Ocean University of China · CNQingdao University · CNQingdao National Laboratory for Marine Science and Technology · CNUniversidade Estadual de Maringá · BRUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate whether combinations of sulbactam, meropenem, and polymyxin-B could reduce or close the gap of mutant selection window (MSW) of individual antibiotics against

Indexed as

Acinetobacter baumanniimeropenemOXA-23pharmacodynamicspolymyxin-Bsulbactam

Identifiers

PMID36483204
PMCPMC9723340
OpenAlexW4311027028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.