Evidence map›Paper›PMID 36483091›Full record

ArticleTherapeutics and clinical risk management2022

Drug-Related Problems in Pulmonary Hypertension with Valvular Heart Disease.

Farizan Abdul-Ghaffar, Adyani Md Redzuan, Mohd Makmor-Bakry, Mohamad Arif Muhamad Nor

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Farizan Abdul-GhaffarFaculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.ORCID 0000-0002-1346-7115
Adyani Md RedzuanFaculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.ORCID 0000-0002-8125-8462
Mohd Makmor-BakryFaculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.ORCID 0000-0002-0592-0645
Mohamad Arif Muhamad NorDepartment of Cardiothoracic, Hospital Serdang, Kajang, Malaysia.
National University of Malaysia · MYSerdang Hospital · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The occurrence of drug-related problems (DRPs) and their causes specifically among pulmonary hypertension (PH) with valvular heart disease (VHD) has not been evaluated and is unknown. Therefore, this study aimed to determine the percentage of occurrence, types, and causes of DRPs among PH with VHD patients. Patients and Methods: An observational retrospective study was conducted at Cardiology Centre, Hospital Serdang, from 1st January to 30th April 2021. Data were collected from medication charts, medical progress notes, laboratory and operative charts through electronic Health Information System (eHIS). The types and causes of DRPs were identified and classified based on Pharmaceutical Care Network of Europe's (PCNE) classification system V9.02. The data were analyzed using descriptive statistics. Results: All patients (100%) experienced at least one DRP. Total number of DRPs identified was 120 encounters which were associated with 503 causes. The majority of problems were related to treatment effectiveness (59.1%) and treatment safety (33.4%). The causes of DRPs are mainly related to inappropriate monitoring including therapeutic drug monitoring (18.6%), inappropriate combination of drugs, or drugs and dietary/herbal supplement (10.3%), drug dose was too high (8.9%), drug dose was too low (8.2%) and inappropriate timing of administration or dosing intervals (7.7%). Conclusion: The percentage of DRP occurrence was high in the studied population. Treatment effectiveness and treatment safety issues were the main DRPs identified with various preventable causes. The findings may be useful to guide the planning of measures to prevent and solve future DRPs in the population.

Indexed as

adverse drug reactionspharmaceutical caretreatment effectivenesstreatment safety

Identifiers

PMID36483091
PMCPMC9724581
OpenAlexW4311025753

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.