Evidence map›Paper›PMID 36483014›Full record

ArticleiScience2022

Dynamic immune markers predict HIV acquisition and augment associations with sociobehavioral factors for HIV exposure.

Rachel A Bender Ignacio, Sayan Dasgupta, Rogelio Valdez, Urvashi Pandey, Siavash Pasalar, Ricardo Alfaro, Florian Hladik, Germán Gornalusse, Javier R Lama, Ann Duerr

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel A Bender IgnacioDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98104, USA.
Sayan DasguptaVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Rogelio ValdezCase Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Urvashi PandeyDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA.
Siavash PasalarVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Ricardo AlfaroCentro de Investigaciones Tecnológicas Biomédicas y Medioambientales, Universidad Nacional Mayor de San Marcos, Bellavista, Lima 07006, Peru.
Florian HladikVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Germán GornalusseDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA.
Javier R LamaAsociación Civil Impacta Salud y Educación, Lima 15063, Peru.
Ann DuerrVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.

Funding

NCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5M
Modulating the Impact of Critical Events in Early HIV Infection: Effect of Early ART Initiation and Alcohol UseR01DA040532 · NIDA · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DUERR, ANN C · 2015 to 2019
$8.0M
HIV Testing and Treatment to Prevent Onward HIV Transmission among High-risk MSMR01DA032106 · NIDA · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DUERR, ANN C · 2011 to 2015
$6.6M
Determining the component causes of systemic immune activation that moderate HIV acquisition and establishment of the latent viral reservoirK23AI129659 · NIAID · UNIVERSITY OF WASHINGTON · PI BENDER IGNACIO, RACHEL ANN · 2017 to 2021
$868k
NCATS NIH HHS KL2 TR002317NIAID NIH HHS K23 AI129659NIDA NIH HHS R01 DA032106NIDA NIH HHS R01 DA040532
6 · The paper itself

Abstract

Prior studies attempting to link biomarkers of immune activation with risk of acquiring HIV have relied on cross sectional samples, most without proximity to HIV acquisition. We created a nested case-control study within the

Indexed as

Health sciencesMachine learningVirology

Identifiers

PMID36483014
PMCPMC9722478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.