ArticleWorld journal of biological chemistry2022
Serum leptin level in Sudanese women with unexplained infertility and its relationship with some reproductive hormones.
Article in World journal of biological chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Modulatory Effects of Antioxidant Supplementation on Serum Oxidative Stress Biomarkers MDA and T-AOC in Females with Unexplained Infertility.Antioxidants (Basel, Switzerland) · 2026Article
- Serum VEGF Potential as a Biomarker for Diagnosis of Female Unexplained Infertility: Does Atopy Matter?International journal of molecular sciences · 2025Observational
- Key predictors of fertility: Exploring the role of Vitamin-D.Pakistan journal of medical sciences · 2024Article
- Characterization and risk factors for unexplained female infertility in Sudan: A case-control study.World journal of methodology · 2023Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
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Abstract
backgroundThe excessive concentration of leptin has negative effects on all aspects of female reproduction. Despite this established relationship, the exact role of leptin in women's fertility is not clear enough and needs more clarification.
aimTo evaluate the serum leptin levels in Sudanese women and to ascertain the relationship between serum leptin levels and unexplained infertility (UI).
methodsA matched (age and body mass index) case-control study was conducted from March 2021 to February 2022. The study samples were 210 women with UI and 190 fertile women of reproductive age who were attending the maternity hospitals and fertility clinics in Khartoum state Sudan. The serum concentration of leptin and other serum biomarkers were determined using enzyme-linked immunosorbent assays.
resultsThe results showed that there was a highly statistically significant difference between the two groups (
conclusionThis study reveals that leptin could be a potential biomarker for UI in Sudanese women and it may be useful for identifying women with a high risk of infertility.
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