Evidence map›Paper›PMID 36482968›Full record

ArticlebioRxiv : the preprint server for biology2022

Non-invasive diagnostic method to objectively measure olfaction and diagnose smell disorders by molecularly targeted fluorescent imaging agent.

Dauren Adilbay, Junior Gonzales, Marianna Zazhytska, Paula Demetrio de Souza Franca, Sheryl Roberts, Tara Viray, Raik Artschwager, Snehal Patel, Albana Kodra, Jonathan B Overdevest and 7 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Dauren AdilbayDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Junior GonzalesDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marianna ZazhytskaMortimer B. Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
Paula Demetrio de Souza FrancaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sheryl RobertsDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Tara VirayDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Raik ArtschwagerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Snehal PatelDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Albana KodraMortimer B. Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
Jonathan B OverdevestDepartment of Otolaryngology- Head and Neck Surgery, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Chun Yuen ChowInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.
Glenn F KingInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.
Sanjay K JainCenter for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alvaro A OrdonezCenter for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Laurence S CarrollCenter for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Thomas ReinerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nagavarakishore PillarsettyDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USJohns Hopkins University · USAustralian Research Council · AUColumbia University Irving Medical Center · USMIND Research Institute · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Radioiodinated Multifunctional PARP1 Imaging Probes for Diagnosis and TherapyR01CA204441 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI PILLARSETTY, NAGAVARAKISHORE · 2016 to 2020
$2.9M
Development and validation of an intraoperative imaging agent for the peripheral nervous systemR01EB029769 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI PILLARSETTY, NAGAVARAKISHORE · 2020 to 2023
$2.2M
Neurocognitive & neuropsychiatric impact of chemosensory alterations: Implications of olfactory dysfunction in COVID-19K23DC019678 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OVERDEVEST, JONATHAN B · 2021 to 2025
$893k
Development of multimodal agents from natural spider peptides for prostate cancer via sodium-channel NaV1.7K99GM145587 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI GONZALES-AREVALO, JUNIOR ARTURO · 2021 to 2022
$158k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA204441NIBIB NIH HHS R01 EB029769NIDCD NIH HHS K23 DC019678NIGMS NIH HHS K99 GM145587
6 · The paper itself

Abstract

The sense of smell (olfaction) is one of the most important senses for animals including humans. Despite significant advances in the understanding mechanism of olfaction, currently, there are no objective non-invasive methods that can identify loss of smell. Covid-19-related loss of smell has highlighted the need to develop methods that can identify loss of olfaction. Voltage-gated sodium channel 1.7 (Na

Identifiers

PMID36482968
PMCPMC9727758
OpenAlexW3202726793

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.