Evidence map›Paper›PMID 36482768›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2023

The use of residual serum samples to perform serological surveillance of severe acute respiratory syndrome coronavirus 2 in Dili and regional areas of Timor-Leste.

Nevio Sarmento, Lourenço C Ico, Sarah L Sheridan, Maria Y Tanesi, Celia G Santos, Ismael Barreto, Nelia Gomes, Tessa Oakley, Anthony D K Draper, Nicholas S S Fancourt and 4 more

Abstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The COVID-19 laboratory response in Timor-Leste; a story of collaboration.The Lancet regional health. Southeast Asia · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nevio SarmentoGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Lourenço C IcoGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Sarah L SheridanNational Centre for Immunisation Research and Surveillance, Westmead, NSW 2145, Australia.
Maria Y TanesiGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Celia G SantosDepartment of Internal Medicine, Hospital Nacional Guido Valadares, Dili, Timor-Leste.
Ismael BarretoGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Nelia GomesGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Tessa OakleyGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Anthony D K DraperGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Nicholas S S FancourtGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Jennifer YanGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Kristine MacartneyNational Centre for Immunisation Research and Surveillance, Westmead, NSW 2145, Australia.
Joshua R FrancisGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.
Paul ArkellGlobal and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLack of access to diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can limit disease surveillance in remote areas. Serological surveillance can indicate the true extent and distribution of infections in such settings.

methodsThis study monitored SARS-CoV-2 seroprevalence in residual serum samples salvaged from laboratories at five healthcare facilities across Timor-Leste from March to October 2021.

resultsSeroprevalence increased from 8.3% to 87.0% during the study period. Potential immunity gaps were identified among children aged 0-15 y (who had not been eligible for vaccination) and individuals aged >60 y.

conclusionsEfforts to vaccinate vulnerable individuals including older people should be maintained. Residual serum samples can be analysed to give local, contemporary information about the extent and distribution of antibodies to infections, especially SARS-CoV-2, in areas where epidemiological information is limited.

Indexed as

COVID-19AgedAntibodiesAntibodies, ViralChildHumansSARS-CoV-2Seroepidemiologic StudiesTimor-LesteAntibodiesAntibodies, ViralCOVID-19remote areasresidual serumSARS-CoV-2serological surveillance

Identifiers

PMID36482768
PMCPMC10069296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.