Evidence map›Paper›PMID 36482429›Full record

ArticleBMC public health2022

Antimicrobial resistance of enteric pathogens in the Military Health System, 2009 - 2019.

Hayley Ashbaugh, Connor D Pomeroy, Mona Baishya, Kathleen Creppage, Sara Bazaco, Myles Johnson, Kenji Matsumoto, Upendra Bhattarai, Nicholas Seliga, Paul Graf and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Hayley AshbaughWalter Reed Army Institute of Research, U.S. Army Medical Research Directorate-Georgia, 99 Kakheti Highway, 0198, Tbilisi, Georgia. hayley.ashbaugh@gmail.com.
Connor D PomeroyOak Ridge Institute for Science and Education, Defense Centers for Public Health - Portsmouth, 620 John Paul Jones Circle, Suite 1100, Portsmouth, VA, 23704, USA.
Mona BaishyaOak Ridge Institute for Science and Education, Defense Centers for Public Health - Portsmouth, 620 John Paul Jones Circle, Suite 1100, Portsmouth, VA, 23704, USA.
Kathleen CreppagePublic Health Directorate, Armed Forces Health Surveillance Division, Global Emerging Infections Surveillance Branch, 11800 Tech Road, Silver Spring, MD, 20904, USA.
Sara BazacoPublic Health Directorate, Armed Forces Health Surveillance Division, Global Emerging Infections Surveillance Branch, 11800 Tech Road, Silver Spring, MD, 20904, USA.
Myles JohnsonDeloitte Consulting LLP, 1919 N Lynn St Suite 1500, Rosslyn, VA, 22209, USA.
Kenji MatsumotoHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Defense Centers for Public Health - Portsmouth, Portsmouth, United States.
Upendra BhattaraiManTech International Corporation, Defense Centers for Public Health - Portsmouth, Portsmouth, United States.
Nicholas SeligaDefense Centers for Public Health - Portsmouth, 620 John Paul Jones Circle, Suite 1100, Portsmouth, VA, 23704, USA.
Paul GrafNaval Health Research Center, San Diego, CA, USA.
Uzo ChukwumaDefense Centers for Public Health - Portsmouth, 620 John Paul Jones Circle, Suite 1100, Portsmouth, VA, 23704, USA.
Armed Forces Health Surveillance Center · USNavy and Marine Corps Force Health Protection Command · USOak Ridge Institute for Science and EducationDeloitte (United States) · USHenry M. Jackson Foundation · USManTech International (United States) · USNaval Medical Research Unit Six · PEUnited States Army · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute diarrhea (AD) can have significant impacts on military troop readiness. Medical providers must understand current trends of enteropathogen antimicrobial resistance (AMR) in service members (SMs) to inform proper, timely treatment options. However, little is known of enteric pathogen profiles across the Military Health System (MHS). The primary objectives of this study were to identify gaps in enteric pathogen surveillance within the MHS, describe the epidemiology of AMR in enteric pathogens, and identify trends across the MHS both within the Continental United States (CONUS) and outside of the Continental United States (OCONUS).

methodsHealth Level 7 (HL7)-formatted laboratory data were queried for all specimens where Salmonella, Shigella, and Campylobacter species, as well as Shiga toxin-producing Escherichia coli (E. coli) (STEC) were isolated and certified between 1 January 2009 - 31 December 2019. Antibiotic susceptibility testing (AST) results were queried and summarized where available. Descriptive statistics were calculated for each organism by specimen source, year, and susceptibility testing availability.

resultsAmong a total of 13,852 enteric bacterial isolates, 11,877 (86%) were submitted from CONUS locations. Out of 1479 Shigella spp. and 6755 Salmonella spp. isolates, 1221 (83%) and 5019 (74%), respectively, reported any susceptibility results through the MHS. Overall, only 15% of STEC and 4% of Campylobacter spp. specimens had AST results available. Comparing AST reporting at CONUS versus OCONUS locations, AST was reported for 1175 (83%) and 46 (78%) of Shigella isolates at CONUS and OCONUS locations, respectively, and for 4591 (76%) and 428 (63%) of Salmonella isolates at CONUS and OCONUS locations, respectively.

conclusionsThis study revealed inconsistent enteropathogen AST conducted across the MHS, with differing trends between CONUS and OCONUS locations. Additional work is needed to assess pathogen-specific gaps in testing and reporting to develop optimal surveillance that supports the health of the force.

Indexed as

Military Health ServicesAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliHumansAnti-Bacterial AgentsAntimicrobial resistanceCampylobacterEnteric pathogensEscherichia coliInfectious disease surveillanceSalmonellaShigella

Identifiers

PMID36482429
PMCPMC9733093
OpenAlexW4311007409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.