ArticleBMC ophthalmology2022
Characteristics of the optic disc in young people with high myopia.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Optic Nerve Head Parameters and Their Associations With Axial Length and Refractive Status in Cynomolgus Macaques.Investigative ophthalmology & visual science · 2026Article
- The Effects of Myopia on Optic Disc Morphology and Retinal Vascular Geometry: A Study of Anisometropic Eyes.Translational vision science & technology · 2026Article
- Effect of peripapillary atrophy on parameters of the optic nerve head, the peripapillary region and the macula in eyes with myopia.International ophthalmology · 2026Article
- Interpupillary Distance and Peripapillary Myopic Changes: A Pilot Study in a Glaucomatous Cohort.Journal of clinical medicine · 2025Article
- Association between myopia and relative peripheral refraction in children with monocular Tilted disc syndrome.BMC ophthalmology · 2025Observational
- Quantifying monochromatic and polychromatic optical blur anisotropy in the periphery of myopes and emmetropes using a radial asymmetry metric.Frontiers in medicine · 2025Article
- Measurement of the Tilt Angle of the Optic Disc Using Spectral-Domain Optical Coherence Tomography and Related Factors in Myopia.Translational vision science & technology · 2024Article
- Lamina Cribrosa Configurations in Highly Myopic and Non-Highly Myopic Eyes: The Beijing Eye Study.Investigative ophthalmology & visual science · 2024Article
- Optic disc characteristics on digital fundus photographs in Saudi children.Neurosciences (Riyadh, Saudi Arabia) · 2024Article
- Relationship between the structure and microcirculation of the optic disc region and myopic traction maculopathy in highly myopic eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Optic Disc Morphology and Paracentral Scotoma in Patients with Open-Angle Glaucoma and Myopia.Journal of clinical medicine · 2023Article
- Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeThis study aimed to investigate the characteristics of the optic disc in adolescents and young adults with high myopia by applying optical coherence tomography angiography.
methodsA total of 112 patients with high myopia (spherical equivalent refraction (SER) ≤ -6.00 D) aged 12 to 30 years old were enrolled in this cross-sectional study. Parapapillary atrophy (PPA) and ovality index from scanning laser ophthalmoscopy images and the degree of optic disc tilt from the optic nerve head (ONH) OCT B-scans were analysed using ImageJ and MATLAB software. Peripapillary retinal nerve fibre layer thickness (pRNFLT) and radial peripapillary capillary vessel density (RPC VD) around the optic disc were obtained from the images of the optic disc angiography scan.
resultsIn young high myopia patients, the PPA area was positively correlated with age, axial length (AL) and pRNFLT (all p < 0.05) and negatively correlated with SER (r = -0.222, p = 0.020). The degree of the optic disc tilt was associated with increasing AL and pRNFLT (all p < 0.05). The disc area was positively correlated with AL, pRNFLT, and RPC VD (all p < 0.05). In the multivariate regression analysis, PPA area was independently associated with the degree of optic disc tilt and disc area. The degree of optic disc tilt was affected by AL and PPA area while the change of disc area was influenced by PPA area and pRNFLT (all p < 0.05).
conclusionIn young patients with high myopia, PPA area, the degree of optic disc tilt and disc area increased with AL and pRNFLT, while decreased with SER. The association between these factors was slightly different in the adolescent and young adult groups. The degree of the optic disc tilt was more associated with AL and SER in the adolescent group while disc area showed more correlated with AL and SER in the young adult group.
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