Evidence map›Paper›PMID 36482075›Full record

ArticleCommunications biology2022

Controlled release of growth factors using synthetic glycosaminoglycans in a modular macroporous scaffold for tissue regeneration.

Z Söderlund, A Ibáñez-Fonseca, S Hajizadeh, J C Rodríguez-Cabello, J Liu, L Ye, E Tykesson, L Elowsson, G Westergren-Thorsson

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Z SöderlundLung Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden. zackarias.soderlund@med.lu.se.ORCID 0000-0002-7150-4025
A Ibáñez-FonsecaLung Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden.ORCID 0000-0002-2223-5041
S HajizadehDivision Pure and Applied Biochemistry, Lund University, Lund, Sweden.
J C Rodríguez-CabelloBIOFORGE Lab, CIBER-BBN, Universidad de Valladolid, Valladolid, Spain.ORCID 0000-0002-3438-858X
J LiuDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Phamarcy, University of North Carolina, Chapel Hill, NC, USA.
L YeDivision Pure and Applied Biochemistry, Lund University, Lund, Sweden.ORCID 0000-0002-3646-4072
E Tykesson *Lung Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden.
L Elowsson *Lung Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden.
G Westergren-ThorssonLung Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Lund University · SEUniversidad de Valladolid · ESUniversity of North Carolina at Chapel Hill · US

Funding

Synthesis and Pharmacological Evaluation of Homogenous Ultra-Low Molecular Weight HeparinsR01HL144970 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, JIAN · 2019 to 2021
$946k
NHLBI NIH HHS R01 HL144970
6 · The paper itself

Abstract

Healthy regeneration of tissue relies on a well-orchestrated release of growth factors. Herein, we show the use of synthetic glycosaminoglycans for controlled binding and release of growth factors to induce a desired cellular response. First, we screened glycosaminoglycans with growth factors of interest to determine k

Indexed as

Endothelial CellsGlycosaminoglycansAnimalsDelayed-Action PreparationsHumansMiceDelayed-Action PreparationsGlycosaminoglycans

Identifiers

PMID36482075
PMCPMC9732287
OpenAlexW4311578573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.