Evidence map›Paper›PMID 36481543›Full record

ArticleSpinal cord series and cases2022

Phenol neurolysis in people with spinal cord injury: a descriptive study.

Radha Korupolu, Aila Malik, Erin Pemberton, Argyrios Stampas, Sheng Li

Open access · bronzeAbstract read
In one paragraph

Article in Spinal cord series and cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Phenol Neurolysis in Pain and Palliative Medicine.Pain practice : the official journal of World Institute of Pain · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Radha KorupoluDepartment of Physical Medicine and Rehabilitation, The University of Texas Health Sciences Center at Houston, Houston, TX, USA. radha.korupolu@uth.tmc.edu.ORCID 0000-0002-7419-6881
Aila MalikDepartment of Physical Medicine and Rehabilitation, The University of Texas Health Sciences Center at Houston, Houston, TX, USA.
Erin PembertonDepartment of Physical Medicine and Rehabilitation, The University of Texas Health Sciences Center at Houston, Houston, TX, USA.
Argyrios StampasDepartment of Physical Medicine and Rehabilitation, The University of Texas Health Sciences Center at Houston, Houston, TX, USA.
Sheng LiDepartment of Physical Medicine and Rehabilitation, The University of Texas Health Sciences Center at Houston, Houston, TX, USA.
Memorial Hermann Institute for Rehabilitation and Research Foundation · USThe University of Texas Health Science Center at Houston · US

Funding

Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
NCATS NIH HHS KL2 TR003168
6 · The paper itself

Abstract

STUDY

designDescriptive study.

objectivesThe study's main objective was to describe the common targets of phenol neurolysis and review the safety and efficacy of the dose used for this spasticity management procedure in people with spinal cord injury (SCI).

settingAn acute rehabilitation hospital.

methodsData from people with SCI who underwent phenol neurolysis procedures for spasticity management between April 2017 and August 2018 were included in this study. We collected demographics and phenol neurolysis procedure-related information.

resultsA total of 66 people with SCI and spasticity underwent phenol neurolysis of 303 nerves over 102 encounters. During these encounters, 97% of procedures were performed using both electrical stimulation and ultrasound guidance. The median (IQR) total volume of 6% aqueous phenol used per encounter was 4.0 (2.0-6.0) ml with a median (IQR) of 1.5 (1.0-2.3) ml per nerve. The most frequent target was the obturator nerve (33%), followed by the pectoral nerves (23%). Immediate post-phenol neurolysis improvement or reduction in spasticity was reported for 92% of all documented encounters. There was no documentation of any post-procedure-related adverse events in this cohort during this specified time frame.

conclusionsOur findings suggest that phenol neurolysis can be safely used to manage spasticity in people with SCI under combined electrical stimulation and ultrasound guidance. Further research is required to assess the procedure's safety, efficacy, and cost-effectiveness on patient-reported outcomes compared to other spasticity interventions.

Indexed as

PhenolSpinal Cord InjuriesHumansPhenol

Identifiers

PMID36481543
PMCPMC9732339
OpenAlexW4311580565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.