Evidence map›Paper›PMID 36481511›Full record

ArticleJournal of molecular and cellular cardiology2023

Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion.

Alexander S Milliken, Jessica H Ciesla, Sergiy M Nadtochiy, Paul S Brookes

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander S MillikenDepartment of Pharmacology and Physiology, University of Rochester Medical Center, USA.
Jessica H CieslaDepartment of Biochemistry, University of Rochester Medical Center, USA.
Sergiy M NadtochiyDepartment of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, USA.
Paul S BrookesDepartment of Pharmacology and Physiology, University of Rochester Medical Center, USA; Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, USA. Electronic address: paul_brookes@urmc.rochester.edu.
University of Rochester Medical Center · US

Funding

SIRT1, Nitro-Lipids and CardioprotectionR01HL071158 · NHLBI · UNIVERSITY OF ROCHESTER · PI BROOKES, PAUL S · 2003 to 2025
$7.7M
Training in Cellular, Biochemical and Molecular SciencesT32GM068411 · NIGMS · UNIVERSITY OF ROCHESTER · PI MAQUAT, LYNNE E · 2005 to 2019
$3.9M
NHLBI NIH HHS R01 HL071158NIGMS NIH HHS T32 GM068411
6 · The paper itself

Abstract

Tissue ischemia results in intracellular pH (pH

Indexed as

IschemiaMetabolomeAnimalsHydrogen-Ion ConcentrationHypoxiaMiceReperfusionAcidosisHypoxiaIschemiaMetabolismpHPurines

Identifiers

PMID36481511
PMCPMC9868090
OpenAlexW4310859778

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.