Evidence map›Paper›PMID 36481272›Full record

ArticlePreventive medicine2023

E-cigarette use during pregnancy and its association with adverse birth outcomes in the US.

Shuo-Yu Lin, Liang Wang, Weiyu Zhou, Panagiota Kitsantas, Xiaozhong Wen, Hong Xue

Open access · greenAbstract read
In one paragraph

Article in Preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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  8. Striking Surge in Lung Cancer Incidence in Children of Early Life.Journal of respiratory biology and translational medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shuo-Yu LinDepartment of Health Administration and Policy, College of Health and Human Services, George Mason University, Fairfax, VA, USA.
Liang WangRobbins College of Health and Human Sciences, Baylor University, Waco, TX, USA.
Weiyu ZhouDepartment of Statistics, Volgenau School of Engineering, George Mason University, Fairfax, VA, USA.
Panagiota KitsantasDepartment of Health Administration and Policy, College of Health and Human Services, George Mason University, Fairfax, VA, USA.
Xiaozhong WenDepartment of Pediatrics, Jacobs School of Medicine & Biomedical Sciences, University of Buffalo, NY, USA. Electronic address: xiaozhon@buffalo.edu.
Hong XueDepartment of Health Administration and Policy, College of Health and Human Services, George Mason University, Fairfax, VA, USA. Electronic address: hxue4@gmu.edu.
George Mason University · USBaylor University · USUniversity at Buffalo, State University of New York · US

Funding

Determinants and health effects of dynamic changes in e-cigarette use before, during, and after pregnancyR21DA053638 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WEN, XIAOZHONG · 2022 to 2023
$470k
Postpartum Smoking Relapse Prevention by Breastfeeding Promotion -R21HD091515 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WEN, XIAOZHONG · 2018 to 2020
$459k
NICHD NIH HHS R21 HD091515NIDA NIH HHS R21 DA053638
6 · The paper itself

Abstract

The popularity of e-cigarette use among young adults is a growing concern. However, little is known about factors associated with e-cigarette use in pregnant women and birth outcomes. In this retrospective cohort study, we evaluated the influence of several factors on behavioral changes in e-cigarette use before and during pregnancy, and assessed the association between e-cigarette use and subsequent birth outcomes among pregnant women. The Population Assessment of Tobacco and Health (PATH) study, a government-sponsored national longitudinal study based in the US, Waves 1 through 4 (2013-2018) were used. Multivariate logistic regressions were conducted to estimate behavioral changes in e-cigarette use during pregnancy and subsequent influence on high-risk birth (e.g., preterm birth, low birth weight, birth defects, etc.) and fetal death. Although pregnant women who quit vaping before pregnancy (OR = 1.14, 95% CI 0.54-2.40) or had any use during pregnancy (OR = 1.19, 95% CI 0.38-3.73) showed non-differential risk of having a high-risk birth in comparison to women who did not initiate vaping, we observed that the usage of mint/menthol flavor was correlated with higher risk of fetus death (OR = 3.27, 95% CI 1.17-9.19). Healthcare providers should encourage e-cigarette users to quit prior to and during early pregnancy.

Indexed as

Electronic Nicotine Delivery SystemsPregnancy ComplicationsPremature BirthTobacco ProductsVapingFemaleFlavoring AgentsHumansInfant, NewbornLongitudinal StudiesPregnancyRetrospective StudiesYoung AdultFlavoring AgentsE-cigarettesHigh-risk birthPregnantSmoking cessationVape flavors

Identifiers

PMID36481272
PMCPMC9888444
OpenAlexW4311420298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.