Evidence map›Paper›PMID 36480745›Full record

ArticleAnalytical chemistry2022

Measuring the Affinities of RNA and DNA Aptamers with DNA Origami-Based Chiral Plasmonic Probes.

Yike Huang, Joonas Ryssy, Minh-Kha Nguyen, Jacky Loo, Susanna Hällsten, Anton Kuzyk

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yike HuangDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.ORCID 0000-0003-2559-432X
Joonas RyssyDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.ORCID 0000-0001-9894-5050
Minh-Kha NguyenDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.ORCID 0000-0003-3456-3162
Jacky LooDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.ORCID 0000-0002-0355-8865
Susanna HällstenDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.
Anton KuzykDepartment of Neuroscience and Biomedical Engineering, School of Science, Aalto University, FI-00076Aalto, Finland.ORCID 0000-0001-8060-6122
Aalto University · FIVietnam National University Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reliable characterization of binding affinities is crucial for selected aptamers. However, the limited repertoire of universal approaches to obtain the dissociation constant (

Indexed as

Aptamers, NucleotideDNADNA ProbesNucleic Acid HybridizationRNASELEX Aptamer TechniqueAptamers, NucleotideDNADNA ProbesRNA

Identifiers

PMID36480745
PMCPMC9773176
OpenAlexW4312082580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.