Evidence map›Paper›PMID 36480564›Full record

ArticlePloS one2022

Post COVID-19 vaccination side effects and associated factors among vaccinated health care providers in Oromia region, Ethiopia in 2021.

Mesfin Tafa Segni, Hailu Fekadu Demissie, Muhammedawel Kaso Adem, Adem Kedir Geleto, Mesfin Wubishet Kelkile, Birhanu Kenate Sori, Melese Lemmi Heyi, Dhabesa Gobena Iticha, Gemechu Shumi Bejiga, Abera Botere Guddisa and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Mesfin Tafa SegniDepartment of Public Health, College of Health Science, Arsi University, Asella, Ethiopia.ORCID 0000-0001-5082-484X
Hailu Fekadu DemissieDepartment of Public Health, College of Health Science, Arsi University, Asella, Ethiopia.
Muhammedawel Kaso AdemDepartment of Public Health, College of Health Science, Arsi University, Asella, Ethiopia.
Adem Kedir GeletoDepartment of Agricultural Economics, College of Agriculture and Environmental Science, Arsi University, Asella, Ethiopia.
Mesfin Wubishet KelkileArsi Zone Health Department, Oromia Regional Health Bureau, Asella, Ethiopia.
Birhanu Kenate SoriOromia regional Health Bureau, Addis Ababa, Ethiopia.
Melese Lemmi HeyiOromia regional Health Bureau, Addis Ababa, Ethiopia.
Dhabesa Gobena ItichaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Gemechu Shumi BejigaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Abera Botere GuddisaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Yadeta Ayana SimaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Lemessa Tadesse AmenteOromia regional Health Bureau, Addis Ababa, Ethiopia.
Dereje Abdena BayisaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Mengistu Bekele HurisaOromia regional Health Bureau, Addis Ababa, Ethiopia.
Tesfaye Kebebew JiruOromia regional Health Bureau, Addis Ababa, Ethiopia.
Oromiyaa Regional Health Bureau · ETArsi University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere Acute Respiratory Syndrome (SARS COV-2) known as COVID-19 since its outbreak in 2019, more than 375 and 5.6 million were infected and dead, respectively. Its influence in all disciplines stimulated different industries to work day to night relentlessly to develop safe and effective vaccines to reduce the catastrophic effect of the disease. With the increasing number of people globally who have been vaccinated, the reports on possible adverse events have grown and gained great public attention. This study aims to determine post-COVID-19 vaccination adverse effects and associated factors among vaccinated Health care providers in the Oromia region, Ethiopia in 2021.

methodsA cross-sectional study was conducted among 912 health care workers working in government hospitals in the central Oromia region from November 20 to December 15/2021. Respondents absent from work due to different reasons were excluded during the interview. The outcome variable was COVID-19 side effects (response as Yes/No). A descriptive analysis displayed findings in the form of the frequencies and percentages, and logistic regression was employed to see the association of different variables with side effects experienced.

resultOverall, 92.1% of the participants experienced side effects either in 1st or 2nd doses of post-COVID-19 vaccination; 84.0% and (71.5%) of participants experienced at least one side effect in the 1st and 2nd dose of the vaccines, respectively. COVID-19 infection preventive protocols like keeping distance, hand wash using soap, wearing mask and using sanitizer were decreased post vaccination. About 74.3% of the respondents were worried about the adverse effects of the COVID-19 vaccine they received. The majority (80.2%) of the respondent felt fear while receiving the vaccine and 22.5% of the respondents suspect the effectiveness of the vaccine they took. About 14.8% of the vaccinated Health workers were infected by COVID-19 post-vaccination. Engaging in moderate physical activity and feeling fear when vaccinated were the independent factors associated with reported side effects of post-COVID-19 vaccination using multiple logistic regression. Respondents who did not engage in physical activity were 7.54 fold more likely to develop post-COVID-19 vaccination side effects compared to those who involved at least moderate-intensity physical activity[AOR = 7.54, 95% CI;2.46,23.12]. The odds of experiencing side effects among the respondents who felt fear when vaccinated were 10.73 times compared not felt fear (AOR = 10.73, 95% CI; 2.47,46.64), and similarly, those who felt little fear were 4.28 times more likely to experience side effects(AOR = 4.28, 95% CI; 1.28, 14.39).

conclusionSignificant numbers of the respondents experienced side effects post COVID-19 vaccination. It is recommended to provide pre-awareness about the side effects to reduce observed anxiety related to the vaccine. It is also important to plan monitoring and evaluation of the post-vaccine effect using standard longitudinal study designs to measure the effects directly.

Indexed as

COVID-19Drug-Related Side Effects and Adverse ReactionsCOVID-19 VaccinesCross-Sectional StudiesHealth PersonnelHumansLongitudinal StudiesCOVID-19 Vaccines

Identifiers

PMID36480564
PMCPMC9731451
OpenAlexW4311575804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.