Evidence map›Paper›PMID 36480453›Full record

ArticleVeterinary medicine and science2023

Comparing the effects of intravenous injection and intranasal atomisation of detomidine in sheep.

Touran Tahmasbi, Abbas Raisi, Amir Zakian, Majid Khaldari

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Touran TahmasbiFaculty of Veterinary Medicine, Department of Clinical Sciences, Lorestan University, Khorramabad, Iran.
Abbas RaisiFaculty of Veterinary Medicine, Department of Clinical Sciences, Lorestan University, Khorramabad, Iran.ORCID https://orcid.org/0000-0001-8769-4284
Amir ZakianFaculty of Veterinary Medicine, Department of Clinical Sciences, Lorestan University, Khorramabad, Iran.ORCID https://orcid.org/0000-0002-7535-4749
Majid KhaldariFaculty of Agriculture, Department of Animal Husbandry, Lorestan University, Khorramabad, Iran.
Lorestan University · IR

Funding

Lorestan University LU-9411511008-21
6 · The paper itself

Abstract

backgroundDetomidine is an α-2 agonist sedative drug which reduces the release of norepinephrine in nerves. Administering this drug through intranasal (IN) route could cause direct transmission to the central nervous system. Therefore, IN administration of detomidine would decrease the side effects and the onset of sedation.

objectivesIn this study, IN administration of detomidine in sheep through an atomiser was compared to its IV administration.

methodsFifteen mature female sheep with an approximate weight of 49.53 ± 1.72 kg were used. They were randomly divided into three groups: (1) atomising 10 μg/kg (IND

resultsBradycardia and the percentage of reduction from the baseline value in the respiratory rate were lower in the IND

conclusionsOur findings revealed that IN atomisation of detomidine triggers similar sedation as its IV administration, which could be used as an alternative method.

Indexed as

Hypnotics and SedativesImidazolesAnimalsFemaleInjections, IntravenousSheepdetomidineHypnotics and SedativesImidazolesatomisercardiopulmonarydetomidineintravenoussedation

Identifiers

PMID36480453
PMCPMC9857010
OpenAlexW4310946937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.