Evidence map›Paper›PMID 36479714›Full record

ArticleClinical cardiology2023

Use of machine learning models to predict in-hospital mortality in patients with acute coronary syndrome.

Rong Li, Lan Shen, Wenyan Ma, Bo Yan, Wenchang Chen, Jie Zhu, Linfeng Li, Junyi Yuan, Changqing Pan

Abstract read
In one paragraph

Article in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rong LiClinical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Lan ShenClinical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wenyan MaClinical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Bo YanClinical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Wenchang ChenYidu Cloud Technology Inc., Beijing, China.
Jie ZhuYidu Cloud Technology Inc., Beijing, China.
Linfeng LiYidu Cloud Technology Inc., Beijing, China.
Junyi YuanInformation Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Changqing PanHospital's Office, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.

Funding

Information Development Project of Shanghai Economic and Information Commission 202002009
6 · The paper itself

Abstract

backgroundCardiovascular diseases are a significant health burden with the prevalence increasing worldwide. Thus, a highly accurate assessment and prediction of death risk are crucial to meet the clinical demand. This study sought to develop and validate a model to predict in-hospital mortality among patients with the acute coronary syndrome (ACS) using nonlinear algorithms.

methodsA total of 2414 ACS patients were enrolled in this study. All samples were divided into five groups for cross-validation. The logistic regression (LR) model and XGboost model were applied to predict in-hospital mortality. The results of two models were compared between the variable set by the global registry of acute coronary events (GRACE) score and the selected variable set.

resultsThe in-hospital mortality rate was 3.5% in the dataset. Model performance on the selected variable set was better than that on GRACE variables: a 3% increase in area under the receiver operating characteristic (ROC) curve (AUC) for LR and 1.3% for XGBoost. The AUC of XGBoost is 0.913 (95% confidence interval [CI]: 0.910-0.916), demonstrating a better discrimination ability than LR (AUC = 0.904, 95% CI: 0.902-0.905) on the selected variable set. Almost perfect calibration was found in XGBoost (slope of predicted to observed events, 1.08; intercept, -0.103; p < .001).

conclusionsXGboost modeling, an advanced machine learning algorithm, identifies new variables and provides high accuracy for the prediction of in-hospital mortality in ACS patients.

Indexed as

Acute Coronary SyndromeHospital MortalityHumansMachine LearningRetrospective StudiesRisk Assessmentacute coronary syndromein-hospital mortalitylogistic regressionmachine learningXGBoost

Identifiers

PMID36479714
PMCPMC9933107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.