ArticleTransfusion2023
The healthy donor effect and survey participation, becoming a donor and donor career.
Article in Transfusion, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- The effect of plasma donation frequency on total serum protein, immunoglobulin G and donor safety: A non-inferiority randomized controlled trial.Vox sanguinis · 2025Trial
- Serum calcitonin gene-related peptide in patients with persistent post-concussion symptoms, including headache: a cohort study.Journal of neurology · 2024Trial
- Plasma donation rates and infection risk: A multicentre observational study in Denmark.Vox sanguinis · 2026Observational
- Effect of Hormonal Contraceptives on Circulating Biomarkers of Inflammation, Chemotaxis, Angiogenesis, and Vascular Stress.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Observational
- Article
- Higher uptake of common adult vaccines in Australian blood donors: An analysis of linked registry data.Vox sanguinis · 2026Article
- Representativeness of the Danish Blood Donor Study relative to the general population: a cross-sectional assessment.Scientific reports · 2026Article
- High-density lipoprotein subfractions and risk of future venous thromboembolism-the HUNT study.Research and practice in thrombosis and haemostasis · 2026Article
- Beyond donor eligibility: nutritional and lifestyle heterogeneity and implications for long-term donor health preservation.Frontiers in nutrition · 2026Article
- The burden of endometriosis on quality of life in Danish women: an analysis of the Danish Blood Donor Study.BMC medicine · 2025Article
- Reassessing Polysaccharide Responsiveness: Unveiling Limitations of Current Guidelines and Introducing the Polysaccharide Responsiveness Percentile Approach.Journal of clinical immunology · 2025Article
- Can Health Literacy Effectively Enhance Blood Donation Rates?Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Detection of SARS-CoV-2 Reinfections Using Nucleocapsid Antibody Boosting.Emerging infectious diseases · 2025Article
- Interpreting the Influence of Using Blood Donor Residual Samples for SARS-CoV-2 Seroprevalence Studies in Japan: Cross-Sectional Survey Study.JMIR public health and surveillance · 2025Article
- Iron deficiency and infection risk in Danish blood donors.Transfusion · 2025Article
- Transfusion-transmissible coinfections among US blood donors.Transfusion · 2024Article
- Effect of SARS-CoV-2 Infection on Selected Parameters of the Apelinergic System in Repeat Blood Donors.Biomedicines · 2024Article
- A serosurvey examining exposure toIJID regions · 2024Article
- Sociodemographic influences on private and professional contact behaviour during the COVID-19 pandemic in Germany: cross-sectional analysis based on a Regional Blood Donor Cohort.BMC research notes · 2024Article
- SARS-CoV-2 vaccination in Canadian blood donors: Insight into donor representativeness of the general population.Vaccine: X · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe healthy donor effect (HDE) is a selection bias caused by the health criteria blood donors must meet. It obscures investigations of beneficial/adverse health effects of blood donation and complicates the generalizability of findings from blood donor cohorts. To further characterize the HDE we investigated how self-reported health and lifestyle are associated with becoming a blood donor, lapsing, and donation intensity. Furthermore, we examined differences in mortality based on donor status. STUDY DESIGN AND
methodsThe Danish National Health Survey was linked to the Scandinavian Donations and Transfusions (SCANDAT) database and Danish register data. Logistic- and normal regression was used to compare baseline characteristics and participation. Poisson regression was used to investigate future donation choices. Donation intensity was explored by the Anderson-Gill model and Poisson regression. Mortality was investigated using Poisson regression.
resultsBlood donors were more likely to participate in the surveys, OR = 2.45 95% confidence interval (2.40-2.49) than non-donors. Among survey participants, better self-reported health and healthier lifestyle were associated with being or becoming a blood donor, donor retention, and to some extent donation intensity, for example, current smoking conveyed lower likelihood of becoming a donor, OR = 0.70 (0.66-0.75). We observed lower mortality for donors and survey participants, respectively, compared with non-participating non-donors.
conclusionWe provide evidence that blood donation is associated with increased likelihood to participate in health surveys, possibly a manifestation of the HDE. Furthermore, becoming a blood donor, donor retention, and donation intensity was associated with better self-reported health and healthier lifestyles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.