Evidence map›Paper›PMID 36479504›Full record

ReviewJournal of preventive medicine and hygiene2022

The role of Mediterranean diet and gut microbiota in type-2 diabetes mellitus associated with obesity (diabesity).

Serpil Ozsoy, Nazife Sultanoglu, Tamer Sanlidag

Open access · greenAbstract readReview
In one paragraph

Review in Journal of preventive medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Gut microbiota: contributing to high CVD prevalence in people living with schizophrenia?European archives of psychiatry and clinical neuroscience · 2026
    Review
  5. The Role of the Gut Microbiome in Type 2 Diabetes Mellitus.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Impact of Plant-Based School Meals on GutInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Review
  12. Healthy Effects of Milk and Dairy Product Consumption in the Mediterranean Area and Japan.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Management of diabesity: Current concepts.World journal of diabetes · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Serpil OzsoyNear East University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Nicosia, Cyprus.
Nazife SultanogluNear East University, Faculty of Medicine, Department of Medical Microbiology and Clinical Microbiology, Nicosia, Cyprus.
Tamer SanlidagNear East University, DESAM Research Institute, Nicosia, Cyprus.
Near East University · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human body is made up of 10¹⁴ human cells and 10¹⁵ bacterial cells, forming a combined structure that is described as a "superorganism". Commensal, symbiotic, and pathogenic microorganisms in the human body, many of which are located inside the intestine, affect health conditions and diseases. An important factor contributing to the development of chronic diseases is dysbiosis, which occurs when the number of pathogenic microorganisms increases. Dysbiosis is associated with increased intestinal permeability, endotoxemia (increased LPS), pro-inflammatory cytokine release, energy harvest, and adiposity, thus being involved in the pathogenesis of disorders like diabetes and obesity. Nutritional habits are the most important environmental factor that affects intestinal microbial composition. A dietary pattern that was proven successful in regulating gut microbiota is the renowned Mediterranean diet, which is characterized by high plant-based foods consumption, moderate fish and dairy products consumption, and low red meat consumption. There is an inverse relationship between adherence to the Mediterranean diet and chronic diseases like obesity and diabetes. In addition to the direct effects of the Mediterranean diet on the pathogenesis of these diseases, it can also be effective in preventing these diseases due to its effects on the intestinal microbiota. It is noted that the number of Bifidobacterium and Bacteroides increases the longer one's eating habit adhere to the Mediterranean diet, and the number of Firmicutes decreases, accordingly, thus supporting the symbiotic distribution in the intestinal microbiota.

Indexed as

Diabetes MellitusDiet, MediterraneanGastrointestinal MicrobiomeChronic DiseaseHumansObesityDiabesityGut MicrobiotaMediterranean dietObesityType-2 Diabetes Mellitus

Identifiers

PMID36479504
PMCPMC9710419
OpenAlexW4311585305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.