Evidence map›Paper›PMID 36479443›Full record

ArticleInternational journal of food science2022

Isoflavone and Antioxidant of Instant Cream Soup Made from Pumpkin and Tempeh and Their Active Compound in Ovariohysterectomy Rat-Induced Alzheimer's Disease.

Budi Setiawan, Salma S Aulia, Ahmad Sulaeman, Clara M Kusharto, Ekowati Handharyani

Open access · goldAbstract read
In one paragraph

Article in International journal of food science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Budi SetiawanDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia.ORCID https://orcid.org/0000-0001-8655-5477
Salma S AuliaNutrition Study Program, Graduate School, IPB University, Bogor, Indonesia.ORCID https://orcid.org/0000-0002-7062-5909
Ahmad SulaemanDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia.ORCID https://orcid.org/0000-0002-9618-7214
Clara M KushartoDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia.ORCID https://orcid.org/0000-0002-6767-7011
Ekowati HandharyaniDepartment of Veterinary Clinic Reproduction and Pathology, Faculty of Veterinary Medicine IPB University, Bogor, Indonesia.ORCID https://orcid.org/0000-0001-8742-4452
IPB University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Menopause period associated with brain function disorders can caused by decreasing estradiol levels and increasing oxidative stress in the body. Antioxidant agents are required to balance oxidative stress in the body. Instant cream soup made from pumpkin and tempeh is a supplementary food containing isoflavone and antioxidant agents. This study is aimed at analyzing the content of antioxidant level and isoflavones (genistein and daidzein) in instant cream soup and their effect on ovariohysterectomy (OVx) rats. Instant pumpkin cream soup with and without tempeh were subjected to isoflavone content and antioxidant analysis. Serum estradiol was analyzed using enzyme-linked immunosorbent assay. Liver concentration of malondialdehyde (MDA) and activities of superoxide dismutase (SOD) were measured by spectrophotometric methods. The study showed that the isoflavone content (genistein 370.86 g/100 g, daidzein 185.61 g/100 g) was only present in the pumpkin instant cream soup with tempeh (IPTS). IPTS has higher antioxidant levels (134.25 mg AEAC/100 g) than instant pumpkin cream soup without tempeh (IPS). In vivo study, experimental rats showed that OVx increased malondialdehyde (MDA) levels up to 5.85-6.07 nmol mL

Identifiers

PMID36479443
PMCPMC9722274
OpenAlexW4310095839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.