Evidence map›Paper›PMID 36479291›Full record

ArticleFrontiers in pediatrics2022

Clinical presentation and transmission of postnatal cytomegalovirus infection in preterm infants.

Jun Eon Lee, Yea Seul Han, Tae-Jung Sung, Dong Hyun Kim, Byung Ok Kwak

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jun Eon LeeDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, South Korea.
Yea Seul HanDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, South Korea.
Tae-Jung SungDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, South Korea.
Dong Hyun KimDepartment of Pediatrics, Inha University School of Medicine, Incheon, South Korea.
Byung Ok KwakDepartment of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, South Korea.
Hallym University Kangnam Sacred Heart Hospital · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preterm infants are at greater risk of developing postnatal cytomegalovirus (CMV) infection with serious symptoms. Breast milk is the main route of CMV transmission in populations with a high seroprevalence. Objectives: This study aimed to investigate the clinical presentation and transmission of postnatal CMV (pCMV) infection Methods: The medical records of 147 preterm infants were reviewed retrospectively, and their clinical characteristics and outcomes were analyzed. Breast milk and infant urine samples were collected every two weeks until discharge, and the kinetics of CMV loads were evaluated using a polymerase chain reaction assay. Results: Seventeen infants (11.6%) were diagnosed with pCMV infection during the study period. In comparison between the pCMV and control groups, the mean birth weight was significantly lower in the pCMV group than in the control group (1084.1 ± 404.8 g vs. 1362.5 ± 553.8 g, Conclusion: Most preterm infants with pCMV infection present a favorable clinical course and outcomes. A high CMV viral load in breast milk is associated with transmission. Further studies are warranted to prevent transmission and severe pCMV infections in preterm infants.

Indexed as

cytomegalovirushuman milkpremature infanttransmissionviral load

Identifiers

PMID36479291
PMCPMC9719915
OpenAlexW4309446037

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.