Evidence map›Paper›PMID 36478964›Full record

ArticleInfection and drug resistance2022

Bacterial and Fungal Superinfections in COVID-19 Patients Hospitalized in an Intensive Care Unit from Timișoara, Romania.

Alexandru Noris Novacescu, Bettina Buzzi, Ovidiu Bedreag, Marius Papurica, Alexandru Florin Rogobete, Dorel Sandesc, Teodora Sorescu, Luminita Baditoiu, Corina Musuroi, Daliborca Vlad and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alexandru Noris Novacescu *Doctoral School, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0002-9829-9412
Bettina BuzziClinic of Anesthesia and Intensive Care, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Ovidiu BedreagClinic of Anesthesia and Intensive Care, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Marius PapuricaClinic of Anesthesia and Intensive Care, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Alexandru Florin RogobeteClinic of Anesthesia and Intensive Care, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Dorel SandescClinic of Anesthesia and Intensive Care, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Teodora SorescuDepartment of Diabetes, Nutrition and Metabolic Diseases, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0002-4086-0991
Luminita Baditoiu *Department of Epidemiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0003-1572-1196
Corina MusuroiDepartment of Microbiology, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Daliborca VladClinical Laboratory, 'Pius Brînzeu' Emergency Clinical County Hospital, Timisoara, Romania.
Monica Licker *Multidisciplinary Research Center on Antimicrobial Resistance, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.ORCID 0000-0002-9245-5883
Victor Babeș University of Medicine and Pharmacy Timișoara · ROSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Critically ill patients hospitalized in the intensive care unit (ICU) have an increased infection risk. The aim of this study was to determine the bacterial and fungal superinfections rate in Coronavirus disease 2019 (COVID-19) patients stationed in the ICU, identify risk factors associated with their development and to determine whether superinfection plays a role in patients' outcome in this population. Patients and Methods: In this retrospective, non-interventional, single centre, cohort study, medical records of 302 consecutive patients with SARS-COV-2 pneumonia admitted into the COVID-19 ICU of the largest university hospital from Western Romania between October 2020 and May 2021, were reviewed, of whom 236 patients met the inclusion criteria. Results: One hundred and nineteen patients developed a superinfection ≥48 h after being admitted to the hospital. Superinfection rate in the ICU was 50.42%. Coagulase-negative Staphylococci (CoNS) and Conclusion: The superinfection rate in COVID-19 patients was high in this study group. Exogenous risk factors were associated with superinfection more than endogenous factors. Only a small percentage of uninfected COVID-19 patients were not prescribed antibiotics during their hospitalization, raising serious concerns regarding the judicious prescribing of antibiotics in viral infections.

Indexed as

bacteriaCOVID-19fungiICUsuperinfectionviral pandemic

Identifiers

PMID36478964
PMCPMC9721122
OpenAlexW4310484694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.