Evidence map›Paper›PMID 36478780›Full record

ReviewTherapeutic advances in gastroenterology2022

A review of the therapeutic management of ulcerative colitis.

Nasar Aslam, Sheng Wei Lo, Rafid Sikafi, Tom Barnes, Jonathan Segal, Philip J Smith, Jimmy K Limdi

Abstract readReview
In one paragraph

Review in Therapeutic advances in gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Chemical Profiling ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  6. Nutrients · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Postoperative detection ofTransplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. A practical approach to positioning therapies in ulcerative colitis.Journal of the Canadian Association of Gastroenterology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nasar AslamDepartment of Gastroenterology, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK.
Sheng Wei LoNorthern Hospital, Epping, VIC, Australia.
Rafid SikafiSt Mark's Hospital, London North West University Healthcare NHS Trust, London, UK.
Tom BarnesSection of IBD - Division of Gastroenterology, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Jonathan SegalNorthern Hospital, Epping, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-9668-0316
Philip J SmithDepartment of Gastroenterology, Royal Liverpool Hospital, Liverpool University Hospitals Foundation NHS Trust, Liverpool, UK.
Jimmy K LimdiSection of IBD - Division of Gastroenterology, Northern Care Alliance NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0002-1039-6251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of uncertain aetiology. The last two decades have seen an expansion in the therapeutic arsenal used to treat UC. This has resulted in improved clinical remission and response rates. Nonetheless, staples in our current medical management originate from trials conducted in the early 20th century. In this review article, we aim to outline the key milestones in the history of the medical management of UC in addition to highlighting promising therapeutic developments for the future.

Indexed as

anti-TNFsbiologicscorticosteroidsinflammatory bowel diseaseulcerative colitis

Identifiers

PMID36478780
PMCPMC9720837

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.