Evidence map›Paper›PMID 36478668›Full record

ArticleAdvanced functional materials2021

Synovial fluid pH sensor for early detection of prosthetic hip infections.

Uthpala Wijayaratna, Sachindra Kiridena, John D Adams, Caleb J Behrend, Jeffrey N Anker

Open access · greenAbstract read
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 45 citations in OpenAlex.

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  10. The application of impantable sensors in the musculoskeletal system: a review.Frontiers in bioengineering and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Uthpala WijayaratnaDepartment of Chemistry, Clemson University, 102 BRC, 105 Collings St., Clemson, SC 29634, USA.
Sachindra KiridenaDepartment of Chemistry, Clemson University, 102 BRC, 105 Collings St., Clemson, SC 29634, USA.
John D AdamsPrisma Health-Upstate, Department of Orthopedic Surgery, Second Floor Support Tower, 701 Grove Road, Greenville, SC 29605, USA.
Caleb J BehrendOrthoArizona, 1675 E. Melrose St., Gilbert, AZ 85297, USA.
Jeffrey N AnkerDepartments of Chemistry and BioEngineering, and Center for Optical Materials Science and Engineering Technology (COMSET), Clemson University, 102 BRC, 105 Collings St., Clemson, SC 29634, USA.
Clemson University · USMelroseWakefield Healthcare · USPrisma Health · US

Funding

Transnational Research Imaging Core (TRI)P30GM131959 · NIGMS · CLEMSON UNIVERSITY · PI VYAVAHARE, NAREN R · 2019 to 2023
$5.9M
Detecting and Monitoring Implant Infection Using X-ray Excited Luminescence Chemical Imaging (XELCI)R01AR070305 · NIAMS · CLEMSON UNIVERSITY · PI ANKER, JEFFREY N · 2016 to 2020
$1.6M
NIAMS NIH HHS R01 AR070305NIGMS NIH HHS P30 GM131959
6 · The paper itself

Abstract

We describe an implantable sensor developed to measure synovial fluid pH for noninvasive early detection and monitoring of hip infections using standard-of-care plain radiography. The sensor was made of a pH responsive polyacrylic acid-based hydrogel, which expands at high pH and contracts at low pH. A radiodense tantalum bead and a tungsten wire were embedded in the two ends of the hydrogel in order to monitor the change in length of the hydrogel sensor in response to pH via plain radiography. The effective pK

Indexed as

hip infectionshydrogelpHplain radiographysynovial fluid

Identifiers

PMID36478668
PMCPMC9725744
OpenAlexW3176696270

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.