Evidence map›Paper›PMID 36478588›Full record

ArticleJournal of veterinary internal medicine2023

Effects of low-dust forages on dust exposure, airway cytology, and plasma omega-3 concentrations in Thoroughbred racehorses: A randomized clinical trial.

Carla J Olave, Kathleen M Ivester, Laurent L Couetil, John Burgess, Jae Hong Park, Abhijit Mukhopadhyay

Open access · goldAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The Role of Omega-3 Fatty Acids in Horses' Nutrition-A Review.Animals : an open access journal from MDPI · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Lipids in Equine Airway Inflammation: An Overview of Current Knowledge.Animals : an open access journal from MDPI · 2024
    Review
  7. Environmental Management of Equine Asthma.Animals : an open access journal from MDPI · 2024
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carla J OlaveDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.
Kathleen M IvesterDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0002-7873-0375
Laurent L CouetilDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0002-1516-6666
John BurgessDepartment of Nutrition Science, College of Health and Human Sciences, Purdue University, West Lafayette, Indiana, USA.
Jae Hong ParkSchool of Health Sciences, College of Health and Human Sciences, Purdue University, West Lafayette, Indiana, USA.
Abhijit MukhopadhyayDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.
Purdue University West Lafayette · US

Funding

Occupational Safety and Health Training GrantT03OH008615 · OH · PURDUE UNIVERSITY · PI WELLS, ELLEN M · 2011 to 2025
$1.7M
C&M ForageGrayson-Jockey Club Research FoundationHaygainNational Institute of Food and Agriculture IND020767AHNIOSH CDC HHS T03 OH008615State of Indiana and PVM Research Account
6 · The paper itself

Abstract

backgroundRacehorses commonly develop evidence of mild asthma in response to dust exposure. Diets deficient in omega-3 polyunsaturated fatty acids (Ω-3) might exacerbate this response. HYPOTHESIS: To compare dust exposure, bronchoalveolar lavage fluid (BALF) cytology, and plasma Ω-3 and specialized pro-resolving mediators (SPM) concentrations amongst racehorses fed dry hay, steamed hay, and haylage. ANIMALS: Forty-three Thoroughbred racehorses.

methodsProspective clinical trial. Horses were randomly assigned to be fed dry hay, steamed hay, or haylage for 6 weeks. Measures of exposure to dust in the breathing zone were obtained twice. At baseline, week-3, and week-6, BALF cytology was examined. Plasma lipid profiles and plasma SPM concentrations were examined at baseline and week 6. Generalized linear mixed models examined the effect of forage upon dust exposure, BALF cytology, Ω-3, and SPM concentrations.

resultsRespirable dust was significantly higher for horses fed hay (least-square mean ± s.e.m. 0.081 ± 0.007 mg/m CONCLUSIONS AND CLINICAL IMPORTANCE: Steamed hay and haylage reduce dust exposure compared with dry hay, but only haylage increased the ratio of anti-inflammatory to pro-inflammatory lipids while reducing BAL neutrophil proportions within 6 weeks.

Indexed as

DustHorse DiseasesAnimalsBronchoalveolar Lavage FluidDietHorsesProspective StudiesRespiratory SystemDustairwayasthmahaylageinflammationneutrophilsresolutionrespiratory tract

Identifiers

PMID36478588
PMCPMC9889630
OpenAlexW4310962189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.