ArticleAnnals of dermatology2022
Analysis of the Microbiome of the Ear Canal in Normal Individuals and Patients with Chronic Otitis Externa.
Article in Annals of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- The Importance of Ear Canal Microbiota and Earwax in the Prevention of Outer Ear Infections.International journal of molecular sciences · 2026Review
- Microbiome and its Association with Diseases of the Ear, Nose and Pharynx.Endocrine, metabolic & immune disorders drug targets · 2026Review
- Association between theMicrobiology spectrum · 2025Article
- The role of the microbiome in allergic dermatitis-related otitis externa: a multi-species comparative review.Frontiers in veterinary science · 2024Review
- Changes functional prediction of ear canal flora in chronic bacterial otitis externa.Frontiers in cellular and infection microbiology · 2024Article
- Perspectives of Italian Physicians and Patients in the Treatment of Otitis Externa: A Real-Life Study.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRecently, microbiome research has been actively conducted for various skin areas. However, no study has yet compared the microbiome of bacteria and fungi in the ear canal of healthy individuals and patients with chronic otitis externa in Korea.
objectiveThis study aimed to investigate the difference in the distribution of fungal and bacterial microbial communities in ear canal samples of healthy individuals and patients with chronic otitis externa.
methodsIn 24 patients with bilateral chronic otitis externa and 24 healthy controls, cotton swabs were used to obtain samples from the bilateral ear canal. To characterize the fungal and bacterial communities, we sequenced and analyzed the 16S rRNA V4-V5 and ITS1 regions using Quantitative Insights into Microbial Ecology 2, respectively.
resultsThe alpha diversity analysis for bacteria and fungi confirmed that both richness and evenness decreased in the patient group. The beta diversity analysis for bacteria confirmed that these parameters differed between the control and patient groups. The beta diversity analysis for fungi showed no difference between the groups.
conclusionWe observed different skin microbiomes in the patients with chronic otitis externa compared with those in the healthy individuals.
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