Evidence map›Paper›PMID 36478420›Full record

ArticleChemistryOpen2022

Precursor-Directed Synthesis of Apoptosis-Initiating N-Hydroxyalkyl Phenylbenzoisoquinolindione Alkaloids.

Yu Chen, Hans-Martin Dahse, Christian Paetz, Bernd Schneider

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yu ChenMax-Planck-Institute for Chemical Ecology, NMR/Biosynthesis Group, Hans-Knöll-Straße 8, 07745, Jena, Germany.ORCID 0000-0001-7349-0686
Hans-Martin DahseLeibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (Leibniz-HKI), Beutenbergstraße 11a, 07745, Jena, Germany.ORCID 0000-0003-2012-4388
Christian PaetzMax-Planck-Institute for Chemical Ecology, NMR/Biosynthesis Group, Hans-Knöll-Straße 8, 07745, Jena, Germany.ORCID 0000-0002-5776-7574
Bernd SchneiderMax-Planck-Institute for Chemical Ecology, NMR/Biosynthesis Group, Hans-Knöll-Straße 8, 07745, Jena, Germany.ORCID 0000-0003-4788-1565
Max Planck Institute for Chemical Ecology · DEChinese Academy of Sciences · CNLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A precursor-directed approach to access N-hydroxyalkyl phenylbenzoisoquinolindiones (PBIQs) has been developed. Incubation of plant material of Xiphidium caeruleum with hydroxylamines of various chain lengths (C

Indexed as

ApoptosisHeLa CellsHumansantiproliferative effectapoptosiscytotoxicityphenylbenzoisoquinolindioneprecursor-directed synthesis

Identifiers

PMID36478420
PMCPMC9728486
OpenAlexW4311175745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.