Evidence map›Paper›PMID 36477695›Full record

ArticleAnaesthesia2023

The association between iron deficiency and outcomes: a secondary analysis of the intravenous iron therapy to treat iron deficiency anaemia in patients undergoing major abdominal surgery (PREVENTT) trial.

T Richards, L F Miles, B Clevenger, A Keegan, S Abeysiri, R Rao Baikady, M W Besser, J P Browne, A A Klein, I C Macdougall and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Anaesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 5 countries.

T RichardsDivision of Surgery, University of Western Australia, Perkins South Building, Fiona Stanley Hospital, Murdoch, Perth, WA, Australia.
L F MilesDepartment of Critical Care, Melbourne Medical School, The University of Melbourne, VIC, Australia.
B ClevengerDepartment of Anaesthesia, Royal National Orthopaedic Hospital, Stanmore, UK.
A KeeganDepartment of Haematology, PathWest Laboratory Medicine, King Edward Memorial Hospital, Subiaco, WA, Australia.
S AbeysiriDivision of Surgery, University of Western Australia, Perkins South Building, Fiona Stanley Hospital, Murdoch, Perth, WA, Australia.
R Rao BaikadyDepartment of Anaesthesia, The Royal Marsden NHS Foundation Trust, London, UK.
M W BesserDepartment of Haematology, Addenbrooke's Hospital, Cambridge, UK.
J P BrowneSchool of Public Health, University College Cork, Ireland.
A A KleinDepartment of Anaesthesia and Intensive Care, Royal Papworth Hospital, Cambridge, UK.
I C MacdougallDepartment of Renal Medicine, King's College Hospital, London, UK.
G J MurphyDepartment of Cardiovascular Sciences, University of Leicester, UK.
S D AnkerDepartment of Cardiology, Berlin Institute of Health Centre for Regenerative Therapies; German Centre for Cardiovascular Research partner site Berlin; Charité Universitätsmedizin Berlin, Germany.
D DahlySchool of Public Health, University College Cork, Ireland.
PREVENTT trial collaborators
University College Cork · IEAddenbrooke's Hospital · GBBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEFiona Stanley Hospital · AUKing Edward Memorial Hospital · AUKing's College Hospital · GBPapworth Hospital · GBRoyal Marsden NHS Foundation Trust · GBThe University of Melbourne · AUThe University of Western Australia · AUUniversity College London · GBUniversity of Leicester · GB

Funding

Health Technology Assessment Programme 10/104/06
6 · The paper itself

Abstract

In the intravenous iron therapy to treat iron deficiency anaemia in patients undergoing major abdominal surgery (PREVENTT) trial, the use of intravenous iron did not reduce the need for blood transfusion or reduce patient complications or length of hospital stay. As part of the trial protocol, serum was collected at randomisation and on the day of surgery. These samples were analysed in a central laboratory for markers of iron deficiency. We performed a secondary analysis to explore the potential interactions between pre-operative markers of iron deficiency and intervention status on the trial outcome measures. Absolute iron deficiency was defined as ferritin <30 μg.l

Indexed as

Anemia, Iron-DeficiencyIron DeficienciesFerritinsHemoglobinsHumansPostoperative ComplicationsPreoperative CareTransferrinsFerritinsHemoglobinsTransferrinsanaemiairontransfusion

Identifiers

PMID36477695
PMCPMC10107684
OpenAlexW4311286709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.