Evidence map›Paper›PMID 36477652›Full record

ArticleAIDS and behavior2023

Substance Use and Depression Impede ART Adherence Among Female Sex Workers Living with HIV in the Dominican Republic.

Yan Wang, Tahilin Sanchez Karver, Carla J Berg, Clare Barrington, Yeycy Donastorg, Martha Perez, Hoisex Gomez, Wendy Davis, Noya Galai, Deanna Kerrigan

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Yan WangDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA. yanwang20@gwu.edu.ORCID http://orcid.org/0000-0001-7008-0147
Tahilin Sanchez KarverDepartment of Health, Behavior and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Carla J BergDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Clare BarringtonDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Yeycy DonastorgHIV Vaccine Trials Research Unit, Instituto Dermatologico y Cirugia de la Piel, Santo Domingo, Dominican Republic.
Martha PerezHIV Vaccine Trials Research Unit, Instituto Dermatologico y Cirugia de la Piel, Santo Domingo, Dominican Republic.
Hoisex GomezHIV Vaccine Trials Research Unit, Instituto Dermatologico y Cirugia de la Piel, Santo Domingo, Dominican Republic.
Wendy DavisDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Noya GalaiDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Deanna KerriganDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Milken Institute · USInstituto Dermatológico y Cirugía de Piel "Dr. Huberto Bogaert Díaz" · DOJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · US

Funding

SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Stigma, Cohesion and HIV Outcomes Among Vulnerable Women Across Epidemic SettingsR01MH110158 · NIMH · JOHNS HOPKINS UNIVERSITY · PI KERRIGAN, DEANNA L · 2016 to 2020
$3.6M
NIAID NIH HHS P30 AI117970NICHD NIH HHS P2C HD050924NIMH NIH HHS R01 MH110158
6 · The paper itself

Abstract

Female sex workers (FSW) have worse HIV outcomes in part due to lower anti-retroviral therapy (ART) adherence. Substance use and depression are important barriers to ART adherence, yet few studies have assessed these relationships among FSW in longitudinal studies. Cross-Lagged Panel Models and autoregressive mediation analyses assessed substance use (illicit drug use and alcohol use disorders) in relation to ART non-adherence and the mediation role of depressive symptoms among 240 FSW living with HIV in the Dominican Republic. In annual visits (T1, T2, T3), the majority (70%, 66%, and 53%) reported at-risk drinking and 15%, 13% and 9% used illicit drug during the past 6 months. Most FSW (70%, 62% and 46%) had mild-to-severe depression. Illicit drug use predicted later ART non-adherence. This relationship was not mediated via depressive symptoms. Integrated substance use and HIV care interventions are needed to promote ART adherence and viral suppression among FSW.

Indexed as

AlcoholismHIV InfectionsIllicit DrugsSex WorkersSubstance-Related DisordersDepressionDominican RepublicFemaleHumansMedication AdherenceIllicit DrugsART adherenceDepressionHIVSex workSubstance use

Identifiers

PMID36477652
PMCPMC10225324
OpenAlexW4311283726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.