Evidence map›Paper›PMID 36477635›Full record

ArticleScientific reports2022

Potential in vitro anti-periodontopathogenic, anti-Chikungunya activities and in vivo toxicity of Brazilian red propolis.

Nagela Bernadelli Sousa Silva, Jonathan Henrique de Souza, Mariana Brentini Santiago, Jhennyfer Rodrigues da Silva Aguiar, Daniel Oliveira Silva Martins, Rafael Alves da Silva, Igor de Andrade Santos, Jennyfer A Aldana-Mejía, Ana Carolina Gomes Jardim, Reginaldo Dos Santos Pedroso and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Frontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Nagela Bernadelli Sousa SilvaInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Jonathan Henrique de SouzaInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Mariana Brentini SantiagoInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Jhennyfer Rodrigues da Silva AguiarInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Daniel Oliveira Silva MartinsInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Rafael Alves da SilvaFaculty of Medicine (FAMED), Federal University of Uberlândia, Uberlândia, Brazil.
Igor de Andrade SantosInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Jennyfer A Aldana-MejíaFaculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, Brazil.
Ana Carolina Gomes JardimInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil.
Reginaldo Dos Santos PedrosoTechnical School of Health (ESTES), Federal University of Uberlândia, Uberlândia, Brazil.
Sergio Ricardo AmbrósioExact and Technological Sciences Nucleus, University of Franca (UNIFRAN), Franca, Brazil.
Rodrigo Cássio Sola VenezianiExact and Technological Sciences Nucleus, University of Franca (UNIFRAN), Franca, Brazil.
Jairo Kenupp BastosFaculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, Brazil.
Regina Helena PiresPostgraduate Program in Health Promotion, University of Franca (UNIFRAN), Franca, Brazil.
Carlos Henrique Gomes MartinsInstitute of Biomedical Sciences (ICBIM), Federal University of Uberlândia, Uberlândia, Brazil. carlos.martins2@ufu.br.
Universidade Federal de Uberlândia · BRUniversidade de Franca · BRUniversidade de Ribeirão Preto · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial and viral infections are serious public health issue. Therefore, this study aimed to evaluate the antibacterial, antibiofilm and antiviral potential of the Brazilian Red Propolis (BRP) crude hydroalcoholic extract, fractions, and isolated compounds, as well as their in vivo toxicity. The antibacterial activity was evaluated by determining the Minimum Inhibitory Concentration and the antibiofilm activity by determining the Minimum Inhibitory Concentration of Biofilm (MICB

Indexed as

PropolisAnimalsBrazilCaenorhabditis elegansPlant ExtractsPlant ExtractsPropolis

Identifiers

PMID36477635
PMCPMC9729292
OpenAlexW4311585310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.