Evidence map›Paper›PMID 36477566›Full record

ArticleThe Plant cell2023

Beyond transcription: compelling open questions in plant RNA biology.

Pablo A Manavella, Micaela A Godoy Herz, Alberto R Kornblihtt, Reed Sorenson, Leslie E Sieburth, Kentaro Nakaminami, Motoaki Seki, Yiliang Ding, Qianwen Sun, Hunseung Kang and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Elevating RNA mNational science review · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. RNA-binding proteins orchestrating immunity in plants.The Plant journal : for cell and molecular biology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Focus on RNA biology.The Plant cell · 2023
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 7 countries.

Pablo A ManavellaInstituto de Agrobiotecnología del Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.ORCID 0000-0003-3589-4414
Micaela A Godoy HerzFacultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA), Buenos Aires C1428EHA, Argentina.ORCID 0000-0002-4397-2585
Alberto R KornblihttFacultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Universidad de Buenos Aires (UBA), Buenos Aires C1428EHA, Argentina.ORCID 0000-0003-4322-0831
Reed SorensonSchool of Biological Sciences, University of Utah Salt Lake City 84112, USA.ORCID 0000-0001-8650-0601
Leslie E SieburthSchool of Biological Sciences, University of Utah Salt Lake City 84112, USA.ORCID 0000-0001-6691-2000
Kentaro NakaminamiCenter for Sustainable Resource Science, RIKEN, Kanagawa 230-0045, Japan.ORCID 0000-0003-2713-8280
Motoaki SekiCenter for Sustainable Resource Science, RIKEN, Kanagawa 230-0045, Japan.ORCID 0000-0001-8288-0467
Yiliang DingDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0003-4161-6365
Qianwen SunCenter for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-0111-5400
Hunseung KangDepartment of Applied Biology, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0002-3532-7690
Federico D ArielInstituto de Agrobiotecnología del Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.ORCID 0000-0001-8478-8808
Martin CrespiInstitute of Plant Sciences Paris Saclay IPS2, CNRS, INRA, Université Evry, Université Paris-Saclay, Bâtiment 630, Orsay 91405, France.ORCID 0000-0002-5698-9482
Axel J GiudicattiInstituto de Agrobiotecnología del Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe 3000, Argentina.ORCID 0000-0002-4496-7091
Qiang CaiState Key Laboratory of Hybrid Rice, College of Life Science, Wuhan University, Wuhan 430072, China.ORCID 0000-0001-9219-9608
Hailing JinDepartment of Microbiology and Plant Pathology and Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, California 92507, USA.ORCID 0000-0001-5778-5193
Xiaoqi FengDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.ORCID 0000-0002-4008-1234
Yijun QiCenter for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-7100-1700
Craig S PikaardHoward Hughes Medical Institute, Department of Biology, Indiana University, Bloomington, Indiana 47405, USA.ORCID 0000-0001-8204-7459
Universidad Nacional del Litoral · ARCenter for Life Sciences · CNJohn Innes Centre · GBUniversidad de Buenos Aires · ARUniversity of Utah · USCentre National de la Recherche Scientifique · FRChonnam National University · KRHoward Hughes Medical Institute · USKihara Institute for Biological Research · JPRIKEN Center for Sustainable Resource Science · JPUniversity of California, Riverside · USWuhan University · CN

Funding

Cross-kingdom RNA communications between plant and fungal pathogensR35GM136379 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI JIN, HAILING · 2020 to 2024
$2.1M
Biotechnology and Biological Sciences Research Council BBP0135111Biotechnology and Biological Sciences Research Council BBS0096201Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9773Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9788European Research Council 804981NIGMS NIH HHS R35 GM136379
6 · The paper itself

Abstract

The study of RNAs has become one of the most influential research fields in contemporary biology and biomedicine. In the last few years, new sequencing technologies have produced an explosion of new and exciting discoveries in the field but have also given rise to many open questions. Defining these questions, together with old, long-standing gaps in our knowledge, is the spirit of this article. The breadth of topics within RNA biology research is vast, and every aspect of the biology of these molecules contains countless exciting open questions. Here, we asked 12 groups to discuss their most compelling question among some plant RNA biology topics. The following vignettes cover RNA alternative splicing; RNA dynamics; RNA translation; RNA structures; R-loops; epitranscriptomics; long non-coding RNAs; small RNA production and their functions in crops; small RNAs during gametogenesis and in cross-kingdom RNA interference; and RNA-directed DNA methylation. In each section, we will present the current state-of-the-art in plant RNA biology research before asking the questions that will surely motivate future discoveries in the field. We hope this article will spark a debate about the future perspective on RNA biology and provoke novel reflections in the reader.

Indexed as

Gene Expression RegulationRNABiologyMethylationRNA InterferenceRNA, PlantRNARNA, Plant

Identifiers

PMID36477566
PMCPMC10226580
OpenAlexW4310959824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.