Evidence map›Paper›PMID 36477538›Full record

ArticleNature2022

A transcriptional switch controls sex determination in Plasmodium falciparum.

A R Gomes, A Marin-Menendez, S H Adjalley, C Bardy, C Cassan, M C S Lee, A M Talman

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  8. Molecular mechanisms involved inFrontiers in microbiology · 2026
    Review
  9. Review
  10. TheInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Population genomics ofbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

A R GomesLaboratory of Pathogen Host Interactions UMR 5235, Université de Montpellier and CNRS, Montpellier, France.
A Marin-Menendez *MIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France.
S H Adjalley *Wellcome Sanger Institute, Hinxton, UK.
C Bardy *MIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France.
C Cassan *MIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France.
M C S LeeWellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-4973-0915
A M TalmanMIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France. arthur.talman@ird.fr.ORCID http://orcid.org/0000-0003-2584-3672
Centre National de la Recherche Scientifique · FRWellcome Sanger Institute · GB

Funding

Wellcome TrustWellcome Trust 206194/Z/17/Z
6 · The paper itself

Abstract

Sexual reproduction and meiotic sex are deeply rooted in the eukaryotic tree of life, but mechanisms determining sex or mating types are extremely varied and are only well characterized in a few model organisms

Indexed as

Gene Expression RegulationMalariaMalaria, FalciparumParasitesSex Determination ProcessesTranscription, GeneticAnimalsFemaleHumansMalePlasmodium falciparumReproductionSex Characteristics

Identifiers

PMID36477538
PMCPMC9750867
OpenAlexW4311748029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.