Evidence map›Paper›PMID 36477500›Full record

ArticleBioinformatics (Oxford, England)2023

benchdamic: benchmarking of differential abundance methods for microbiome data.

Matteo Calgaro, Chiara Romualdi, Davide Risso, Nicola Vitulo

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matteo CalgaroDepartment of Biotechnology, University of Verona, Verona 37134, Italy.ORCID 0000-0002-3056-518X
Chiara RomualdiDepartment of Biology, University of Padova, Padova 35131, Italy.ORCID 0000-0003-4792-9047
Davide RissoDepartment of Statistical Sciences, University of Padova, Padova 35121, Italy.ORCID 0000-0001-8508-5012
Nicola VituloDepartment of Biotechnology, University of Verona, Verona 37134, Italy.ORCID 0000-0002-9571-0747

Funding

Cancer Genomics:Integrative and Scalable Solutions in R / BioconductorU24CA180996 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MORGAN, MARTIN T, WALDRON, LEVI · 2014 to 2023
$6.9M
Exploiting Public Metagenomic Data to Uncover Cancer-Microbiome RelationshipsR01CA230551 · NCI · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI Levi Waldron · 2020 to 2026
$3.9M
NCI NIH HHS R01 CA230551NCI NIH HHS U24 CA180996University of Verona
6 · The paper itself

Abstract

summaryRecently, an increasing number of methodological approaches have been proposed to tackle the complexity of metagenomics and microbiome data. In this scenario, reproducibility and replicability have become two critical issues, and the development of computational frameworks for the comparative evaluations of such methods is of utmost importance. Here, we present benchdamic, a Bioconductor package to benchmark methods for the identification of differentially abundant taxa. AVAILABILITY AND IMPLEMENTATION: benchdamic is available as an open-source R package through the Bioconductor project at https://bioconductor.org/packages/benchdamic/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

SoftwareMetagenomicsReproducibility of Results

Identifiers

PMID36477500
PMCPMC9825737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.