Evidence map›Paper›PMID 36477462›Full record

ArticleScientific reports2022

Obesity is associated with early recurrence on breast cancer patients that achieved pathological complete response to neoadjuvant chemotherapy.

Francisco Acevedo, Benjamín Walbaum, Sabrina Muñiz, Militza Petric, Raúl Martínez, Constanza Guerra, Marisel Navarro, Miguel Córdova-Delgado, Mauricio P Pinto, Cesar Sánchez

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Resistance to neoadjuvant chemotherapy in breast cancers: a metabolic perspective.Journal of experimental & clinical cancer research : CR · 2025
    Review
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Francisco AcevedoDepartment of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 6th FL. Rm 608, 8330077, Santiago, Chile.
Benjamín WalbaumDepartment of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 6th FL. Rm 608, 8330077, Santiago, Chile.
Sabrina MuñizDivision of Oncological Surgery, Dr. Sotero del Rio Hospital and Healthcare Complex, Santiago, Chile.
Militza PetricDivision of Oncological Surgery, Dr. Sotero del Rio Hospital and Healthcare Complex, Santiago, Chile.
Raúl MartínezDivision of Oncological Surgery, Dr. Sotero del Rio Hospital and Healthcare Complex, Santiago, Chile.
Constanza GuerraDivision of Oncological Surgery, Dr. Sotero del Rio Hospital and Healthcare Complex, Santiago, Chile.
Marisel NavarroDivision of Oncological Surgery, Dr. Sotero del Rio Hospital and Healthcare Complex, Santiago, Chile.
Miguel Córdova-DelgadoDepartment of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 6th FL. Rm 608, 8330077, Santiago, Chile.
Mauricio P PintoDepartment of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 6th FL. Rm 608, 8330077, Santiago, Chile.
Cesar SánchezDepartment of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 6th FL. Rm 608, 8330077, Santiago, Chile. cgsanchezr@gmail.com.
Complejo Asistencial Sótero del Río · CLPontificia Universidad Católica de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathological complete response (pCR) after neoadjuvant chemotherapy (NCT) is associated with good long-term prognosis in breast cancer (BC) patients. However, some patients still recur and eventually die from this disease. For years, clinical stage at diagnosis has been consistently linked to recurrence and survival in the pCR setting. Herein, we aimed to identify other potential predictors of recurrence and survival in patients that achieved pCR. We performed a retrospective analysis of patients diagnosed between 2011 and 2020 in our center. We calculated overall survival (OS), invasive disease-free survival (IDFS), distant disease-free survival (DDFS), and BC-specific survival (BCSS). Among the 241 patients included into our study 36% were obese (Body Mass Index (BMI) > 29.9 kg/m

Indexed as

Breast NeoplasmsNeoadjuvant TherapyFemaleHumansObesityRetrospective Studies

Identifiers

PMID36477462
PMCPMC9729290
OpenAlexW4311576343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.