ArticlePloS one2022
Risk of suicide ideation in comorbid substance use disorder and major depression.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Ketamine for substance use disorders: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Receipt of Pharmacotherapy and Association with Healthcare Utilization Among US Adults with Alcohol or Opioid Use Disorder, 2022-2023.Journal of general internal medicine · 2026Article
- The impact of alcohol use disorder and PTSD comorbidity on risk of suicide attempt.Social psychiatry and psychiatric epidemiology · 2026Article
- Latent class profiles of psychiatric comorbidity among substance-affected Nigerian adolescents: a population-based analysis.BMC psychiatry · 2026Article
- The sources of suicidal ambivalence: favorable and risk factors for suicidal ideation among higher vocational college freshmen-a large sample survey.BMC psychiatry · 2026Article
- Identifying Undiagnosed High-Risk Suicidality Cases by Matching Patients With a Similar Comorbidity Burden: Retrospective Observational Study.JMIR formative research · 2026Observational
- Recent developments in imaging transcriptomics for psychiatric disorders.Psychoradiology · 2026Review
- Kratom Use and Suicidal Thoughts and Behaviors in the United States.Substance use & addiction journal · 2025Article
- Identifying undiagnosed high-risk suicidality cases through comorbidity-adjusted risk modeling.medRxiv : the preprint server for health sciences · 2025Article
- Substance use and psychiatric phenotypes of youth experiencing homelessness: A cluster analysis.The American journal on addictions · 2025Article
- Macro-level determinants of gender differences in the prevalence of major depression and alcohol use disorder in the United States and across Europe.Journal of affective disorders · 2025Article
- Article
- Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care - a pilot study.Frontiers in psychiatry · 2025Article
- A moderated mediation model in assessing links between rumination, emotional reactivity, and suicidal risk in alcohol use disorder.Frontiers in psychiatry · 2025Article
- Article
- Selective Serotonin Reuptake Inhibitors for Cessation of Betel Quid Use in Patients with Major Depressive Disorder in Taiwan.Biomedicines · 2024Article
- Mental Health Treatment Use, Perceived Treatment Need, and Reasons for Non-Use Among U.S. Adults with Serious Suicidal Thoughts During the COVID-19 Pandemic.Community mental health journal · 2024Article
- Association between Alcohol Use Disorder and Suicidal Ideation Using Propensity Score Matching in Chungcheongnam-do, South Korea.Healthcare (Basel, Switzerland) · 2024Article
- Disentangling heterogeneity in substance use disorder: Insights from genome-wide polygenic scores.Translational psychiatry · 2024Article
- Implications of SNP-triggered miRNA dysregulation in Schizophrenia development.Frontiers in genetics · 2024Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuicidal behaviour is commonly associated with major depression (MD) and substance use disorders (SUDs). However, there is a paucity of research on risk for suicide ideation among individuals with comorbid SUDs and MD in the general population.
objectivesThis study investigated the associated risk of suicide ideation in comorbid SUDs-cannabis use disorder (CUD), alcohol use disorder (AUD), drug use disorder (DUD) with major depressive episode (MDE) in a nationally representative sample.
methodsMultilevel logistic regression models were used to analyze the 2012 Canadian Community Health Survey- Mental Health (CCHS-MH) data. This is a cross-sectional survey of nationally representative samples of Canadians (n = 25,113) aged 15 years and older residing in the ten Canadian provinces between January and December 2012. Diagnoses of MDE, AUD, DUD, and CUD were based on a modified WHO-CIDI, derived from DSM-IV diagnostic criteria.
resultsComorbidity was found to be the strongest predictor of suicide ideation. Compared to those with no diagnosis of either a SUD or MDE, individuals with a comorbid diagnosis of AUD with MDE, CUD with MDE, or DUD with MDE were 9, 11 and 16 times more likely to have 12-month suicide ideation respectively. A diagnosis of MDE was a significant predictor of 12-month suicide ideation with about a 7-fold increased risk compared with individuals not diagnosed with either MDE or a SUD.
conclusionSuicide is a preventable public health issue. Our study found a significantly increased risk of suicide ideation among persons who have comorbid SUD with MD. Effective integration of mental health and addictions services could mitigate the risk of suicide and contribute to better outcomes.
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