Evidence map›Paper›PMID 36476944›Full record

ArticleScientific reports2022

The mitochondrial Ca

Akshar Patel, Matthew Simkulet, Soumya Maity, Manigandan Venkatesan, Anastasios Matzavinos, Muniswamy Madesh, B Rita Alevriadou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Modulation of the mitochondrial CaPhysiological reports · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Akshar PatelVascular Mechanobiology Laboratory, Department of Biomedical Engineering, and Center for Cell, Gene, and Tissue Engineering, University at Buffalo - The State University of New York, Buffalo, NY, 14260, USA.
Matthew SimkuletVascular Mechanobiology Laboratory, Department of Biomedical Engineering, and Center for Cell, Gene, and Tissue Engineering, University at Buffalo - The State University of New York, Buffalo, NY, 14260, USA.
Soumya MaityCenter for Mitochondrial Medicine, Department of Medicine, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.
Manigandan VenkatesanCenter for Mitochondrial Medicine, Department of Medicine, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.
Anastasios MatzavinosInstitute for Mathematical and Computational Engineering, Pontifical Catholic University of Chile, Santiago, Chile.
Muniswamy MadeshCenter for Mitochondrial Medicine, Department of Medicine, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.
B Rita AlevriadouVascular Mechanobiology Laboratory, Department of Biomedical Engineering, and Center for Cell, Gene, and Tissue Engineering, University at Buffalo - The State University of New York, Buffalo, NY, 14260, USA. alevri@buffalo.edu.
The University of Texas Health Science Center at San Antonio · USUniversity at Buffalo, State University of New York · USPontificia Universidad Católica de Chile · CL

Funding

Coordination of Pathophysiologic Endothelial Cell Signaling by ROSR01HL086699 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2008 to 2018
$4.3M
Spectral revelations of mitochondrial Ca2+ flux interactomeR01GM109882 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2014 to 2022
$3.3M
Magnesium flux compendium: Discover ligands, channels, and metabolic signalsR35GM145294 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MADESH MUNISWAMY · 2022 to 2026
$2.9M
Mechanisms and therapeutic potential of blocking the mitochondrial Mg2+ channel Mrs2 in obesity and NAFLDR01DK135179 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Joseph A. Baur, MADESH MUNISWAMY · 2023 to 2026
$2.1M
Control of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for AtherosclerosisR01HL142673 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI ALEVRIADOU, BARBARA RITA, MUNISWAMY, MADESH · 2018 to 2021
$2.0M
Inhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injuryR01HL119306 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI MUNISWAMY, MADESH · 2014 to 2017
$1.6M
Essential Role for SPG7 in Mitochondrial Permeability Transition Pore Assembly and FunctionR01GM135760 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2020 to 2021
$613k
Multiphoton Confocal Microscopy for Biomedical ResearchS10RR027327 · NCRR · TEMPLE UNIV OF THE COMMONWEALTH · PI MUNISWAMY, MADESH · 2010 to 2010
$500k
NCRR NIH HHS S10 RR027327NHLBI NIH HHS R01 HL086699NHLBI NIH HHS R01 HL119306NHLBI NIH HHS R01 HL142673NIDDK NIH HHS R01 DK135179NIGMS NIH HHS R01 GM109882NIGMS NIH HHS R01 GM135760NIGMS NIH HHS R35 GM145294
6 · The paper itself

Abstract

The mitochondrial calcium (Ca

Indexed as

Endothelial Cells

Identifiers

PMID36476944
PMCPMC9729216
OpenAlexW4311576341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.