ArticleBMC nursing2022
Effects of a multidisciplinary management program on symptom burden and medication adherence in heart failure patients with comorbidities: A randomized controlled trial.
Article in BMC nursing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Comparative Effectiveness of Non-Pharmacological Interventions for Reducing Heart Failure-Related Unplanned Readmissions: A Systematic Review and Network Meta-Analysis.Journal of clinical medicine · 2026Review
- Bridging the gap in heart failure management: the effect of a cross-disciplinary intervention on guidelines-directed medical therapy in primary care.ESC heart failure · 2026Article
- Facilitators and barriers to volume management interventions in patients with heart failure and hyponatremia: a qualitative study.BMC geriatrics · 2026Article
- Review of clinical medication adherence in patients with schizophrenia.World journal of psychiatry · 2025Review
- Prognostic value of symptom burden as a simple patient-reported outcome measure in older patients with heart failure.Scientific reports · 2025Article
- Effectiveness and medication adherence in patients with ST- elevated myocardial infarction: Persian polypill study.ARYA atherosclerosis · 2024Article
- Multimorbid heart failure (HF) and cardiorenal metabolic (CaReMe) syndrome, exploring integrated models of care: A scoping review.Journal of multimorbidity and comorbidityReview
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComorbidities in heart failure (HF) are a complex clinical challenge. There is little data on the benefits of multidisciplinary postdischarge management programs in such patients. This study aimed to examine the effects of a multidisciplinary management program (MMP) on symptom burden and medication adherence in HF patients with comorbidities.
methodsIn this clinical trial study, 94 HF patients with comorbidities were assigned to intervention (n = 47) and control (n = 47) groups by the stratified-random method. The intervention group underwent MMP supervised by a nurse for two months after discharge, including multi-professional visits, telephone follow-ups, and an educational booklet. Medication adherence and symptom burden were assessed using Morisky Medication Adherence Scale (MMAS) and Edmonton Symptom Assessment Scale (ESAS), respectively, on three occasions: Before discharge, six weeks, and eight weeks after discharge.
resultsBoth groups almost matched at the baseline, and the most frequent comorbidities included myocardial infarction (MI), hypertension, peptic ulcer, and depression, respectively. The interactive effect of time in groups showed that mean changes in total scores of symptom burden and medication adherence were significantly different (P < 0.001) at other time points. A significant increase in medication adherence (P < 0.001) and a significant reduction in the burden of all symptoms were observed in the intervention group compared to the control group from Time 1 to Time 3.
conclusionsThe MMP (targeting comorbidity) is a promising strategy for managing symptoms and medication adherence in HF patients with comorbidities.
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