Evidence map›Paper›PMID 36476318›Full record

Trial reportJournal of psychosocial oncology2023

Hybrid-delivered cognitive behavioral symptom management and activity coaching intervention for patients undergoing hematopoietic stem cell transplant: Findings from intervention development and a pilot randomized trial.

Sarah A Kelleher, Hannah M Fisher, Kelly Hyland, Shannon N Miller, Grace Amaden, Allison Diachina, Alyssa S Pittman, Joseph G Winger, Anthony Sung, Samuel Berchuck and 2 more

2 registry-linked trialsAbstract readRandomized Controlled TrialClinical Trial, Phase II
In one paragraph

Trial report in Journal of psychosocial oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03859765 nacompletednot on this map

Development and Pilot Testing of a Hybrid In Person and mHealth Coping Skills Training Intervention for Symptom Management and Daily Steps in Stem Cell Transplant Patients

TypeinterventionalSponsorDuke UniversityRan2019 to 2021Enrolled40ConditionsStem Cell TransplantArmsHCT Symptoms and Steps
NCT07516314 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients (ACTivate)

TypeinterventionalSponsorAnthony Sung, MDRan2026 to 2031Enrolled476ConditionsStem Cell Transplant PatientsArmsACTivate sessions
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah A KelleherDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
Hannah M FisherDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
Kelly HylandDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.ORCID 0000-0001-9864-5306
Shannon N MillerDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
Grace AmadenDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
Allison DiachinaDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.
Alyssa S PittmanDepartment of Physical Therapy and Occupational Therapy, Duke University Medical Center, Durham, North Carolina, USA.
Joseph G WingerDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.ORCID 0000-0001-6278-2560
Anthony SungDivision of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Samuel BerchuckDepartment of Statistical Science, Duke University, Durham, North Carolina, USA.ORCID 0000-0001-5705-3144
Greg SamsaDepartment of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA.ORCID 0000-0003-2172-1213
Tamara J SomersDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI DONNA NIEDZWIECKI · 1985 to 2026
$174.8M
Development and Pilot Testing of a Hybrid In Person and mHealth Coping Skills Training Intervention for Symptom Management and Daily Steps in Stem Cell Transplant PatientsR21CA235083 · NCI · DUKE UNIVERSITY · PI KELLEHER, SARAH · 2019 to 2020
$385k
NCI NIH HHS L30 CA209705NCI NIH HHS P30 CA014236NCI NIH HHS R21 CA235083
6 · The paper itself

Abstract

objectiveDevelop and pilot test a mobile health (mHealth) cognitive behavioral coping skills training and activity coaching protocol (HCT Symptoms and Steps) for hematopoietic stem cell transplant (HCT) patients.

designTwo-phase, mixed methods study. SAMPLE: HCT patients and healthcare providers.

methodsPhase I was patient (n = 5) and provider (n = 1) focus groups and user testing (N = 5) to develop the HCT Symptoms and Steps protocol. Phase II was a pilot randomized trial (N = 40) to evaluate feasibility, acceptability, and pre-to-post outcomes (e.g., physical disability, pain, fatigue, distress, physical activity, symptom self-efficacy) compared to an education control.

findingsQualitative feedback on symptoms, recruitment strategies, coping skills, and mHealth components (e.g., Fitbit, mobile app) were integrated into the protocol. HCT Symptoms and Steps were feasible and acceptable. Pre-post changes suggest physical disability and activity improved while symptoms (e.g., fatigue, distress) decreased.

conclusionsHCT Symptoms and Steps have strong feasibility and acceptability and shows promise for benefits. Larger, fully-powered randomized trials are needed to examine intervention efficacy. IMPLICATIONS: HCT Symptoms and Steps may reduce physical disability and improve health outcomes post-transplant. CLINICAL TRIAL REGISTRATION NUMBER: NCT03859765.

Indexed as

Hematopoietic Stem Cell TransplantationMentoringCognitionDepressionFatigueHumansPilot ProjectsCancerdistressfatiguehematopoietic stem cell transplantoncologypainphysical activityphysical disabilitysymptom management

Identifiers

PMID36476318
PMCPMC10247893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.