Evidence map›Paper›PMID 36476293›Full record

ArticleLeukemia & lymphoma2023

Cognition in patients treated with targeted therapy for chronic myeloid leukemia: a controlled comparison.

Kelly A Hyland, Sarah L Eisel, Aasha I Hoogland, James C Root, Kris Bowles, Brian James, Ashley M Nelson, Margaret Booth-Jones, Paul B Jacobsen, Tim A Ahles and 2 more

Open access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Chemotherapy-related cognitive impairment and kidney dysfunction.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Kelly A HylandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0001-9864-5306
Sarah L EiselDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Aasha I HooglandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0002-8691-8132
James C RootDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-7332-6165
Kris BowlesDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Brian JamesDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Ashley M NelsonDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1742-3280
Margaret Booth-JonesDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.
Paul B JacobsenHealthcare Delivery Research Program, National Cancer Institute, Bethesda, MD, USA.ORCID 0000-0002-4427-8800
Tim A AhlesDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0001-7353-3711
Brian D GonzalezDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0001-5108-5735
Moffitt Cancer Center · USMemorial Sloan Kettering Cancer Center · USHarvard University · USNational Cancer Institute · MYUniversity of South Florida · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

This controlled comparison study evaluated objective and subjective cognitive function and their relationships with patient-reported symptoms (depression, fatigue, insomnia) in patients receiving tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) and non-cancer controls. Patients with CML in chronic phase treated with the same oral TKI for ≥6 months (

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveSleep Initiation and Maintenance DisordersCognitionFatigueHumansProtein Kinase InhibitorsProtein Kinase Inhibitorschronic myeloid leukemiaCognitionfatigueinsomnia

Identifiers

PMID36476293
PMCPMC10305842
OpenAlexW4310945514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.