Evidence map›Paper›PMID 36475776›Full record

ArticleMicrobiology spectrum2023

Validity of Platelia Aspergillus IgG and Aspergillus Precipitin Test To Distinguish Pulmonary Aspergillosis from Colonization.

Kyota Shinfuku, Junko Suzuki, Keita Takeda, Masahiro Kawashima, Yoshiteru Morio, Yuka Sasaki, Hideaki Nagai, Akira Watanabe, Hirotoshi Matsui, Katsuhiko Kamei

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Guideline
  2. Non-Journal of clinical microbiology · 2026
    Observational
  3. Beyond detection: quantitative interpretation ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Diagnostic performance ofJournal of thoracic disease · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. The diagnostic value of combinedFrontiers in medicine · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Chronic respiratory disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kyota ShinfukuCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.ORCID 0000-0002-3463-9916
Junko SuzukiCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Keita TakedaCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.ORCID 0000-0003-2935-5553
Masahiro KawashimaCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Yoshiteru MorioCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Yuka SasakiCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Hideaki NagaiCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Akira WatanabeDivision of Clinical Research, Medical Mycology Research Center, Chiba University, Chiba, Japan.ORCID 0000-0002-3057-2937
Hirotoshi MatsuiCenter for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.
Katsuhiko KameiDivision of Clinical Research, Medical Mycology Research Center, Chiba University, Chiba, Japan.
Tokyo National Hospital · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When Aspergillus, an ubiquitous, saprophytic fungus, is detected in respiratory tract specimens collected from chronic respiratory disease patients, it is important to determine whether it is a true infection or colonization. We investigated the usefulness of the Bio-Rad Platelia Aspergillus IgG (Platelia Aspergillus IgG) enzyme-linked immunosorbent assay (ELISA) method and the Aspergillus precipitin test to distinguish pulmonary aspergillosis from colonization. Between January 2017 and November 2021, 51 confirmed, untreated pulmonary aspergillosis (33 chronic pulmonary aspergillosis [CPA] and 18 allergic bronchopulmonary aspergillosis [ABPA]) and 77 colonization patients were included in this study. At first, the conventional cutoff value was utilized in assessing the validity of the two antibody tests for distinguishing pulmonary aspergillosis from colonization. The Platelia Aspergillus IgG cutoff value was then reevaluated to fit this situation. Finally, differences in test accuracy dependent on Aspergillus species were assessed for both antibody tests by comparing cases with Aspergillus fumigatus complex and those with non-

Indexed as

Aspergillosis, Allergic BronchopulmonaryPulmonary AspergillosisAntibodies, FungalAspergillusAspergillus fumigatusHumansImmunoglobulin GPrecipitin TestsAntibodies, FungalImmunoglobulin Gallergic bronchopulmonary aspergillosisAspergillus colonizationAspergillus precipitin testchronic pulmonary aspergillosisPlatelia Aspergillus IgG

Identifiers

PMID36475776
PMCPMC9927562
OpenAlexW4310956108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.