Evidence map›Paper›PMID 36475602›Full record

ArticleACS applied materials & interfaces2022

Tunable Self-Assembled Peptide Hydrogel Sensor for Pharma Cold Supply Chain.

Tatiana N Tikhonova, Dana Cohen-Gerassi, Zohar A Arnon, Yuri Efremov, Peter Timashev, Lihi Adler-Abramovich, Evgeny A Shirshin

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tatiana N TikhonovaDepartment of Physics, M.V. Lomonosov Moscow State University, Leninskie gory 1/2, Moscow119991, Russia.
Dana Cohen-GerassiDepartment of Oral Biology, The Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, The Center for Nanoscience and Nanotechnology, The Center for the Physics and Chemistry of Living Systems, Tel Aviv University, Tel Aviv69978, Israel.ORCID 0000-0002-4172-8511
Zohar A ArnonDepartment of Oral Biology, The Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, The Center for Nanoscience and Nanotechnology, The Center for the Physics and Chemistry of Living Systems, Tel Aviv University, Tel Aviv69978, Israel.ORCID 0000-0003-2915-5930
Yuri EfremovWorld-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University 8-2, Trubetskaya St., Moscow119991, Russia.ORCID 0000-0001-7040-253X
Peter TimashevWorld-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University 8-2, Trubetskaya St., Moscow119991, Russia.ORCID 0000-0001-7773-2435
Lihi Adler-AbramovichDepartment of Oral Biology, The Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, The Center for Nanoscience and Nanotechnology, The Center for the Physics and Chemistry of Living Systems, Tel Aviv University, Tel Aviv69978, Israel.ORCID 0000-0003-3433-0625
Evgeny A ShirshinDepartment of Physics, M.V. Lomonosov Moscow State University, Leninskie gory 1/2, Moscow119991, Russia.ORCID 0000-0002-5514-3557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Defrost sensors are a crucial element for proper functioning of the pharmaceutical cold chain. In this paper, the self-assembled peptide-based hydrogels were used to construct a sensitive defrost sensor for the transportation and storage of medications and biomaterials. The turbidity of the peptide hydrogel was employed as a marker of the temperature regime. The gelation kinetics under different conditions was studied to detect various stages of hydrogel structural transitions aimed at tuning the system properties. The developed sensor can be stored at room temperature for a long period, irreversibly indicates whether the product has been thawed, and can be adjusted to a specific temperature range and detection time.

Indexed as

HydrogelsRefrigerationBiocompatible MaterialsPeptidesTemperatureBiocompatible MaterialsHydrogelsPeptidesdefrost sensorfibrillationhydrogelpeptide self-assemblypharma cold chain

Identifiers

PMID36475602
PMCPMC9782340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.