Evidence map›Paper›PMID 36475504›Full record

ArticleLa Medicina del lavoro2022

Effectiveness of prevention of SARS-CoV-2 transmission among unvaccinated Italian healthcare workers.

Giulia Collatuzzo, Ihab Mansour, Catalina Ciocan, Giorgia Ditano, Alessandro Godono, Paola Rossello, Maurizio Coggiola, Enrico Pira, Paolo Boffetta, Working Group On Sars-Cov-Prevention

Abstract read
In one paragraph

Article in La Medicina del lavoro, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness of face masks for reducing transmission of SARS-CoV-2: a rapid systematic review.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia CollatuzzoDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. giulia.collatuzzo@studio.unibo.it.
Ihab MansourDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy . ihab.mansour@unito.it.
Catalina CiocanDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy . catalina.ciocan@unito.it.
Giorgia DitanoDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.. giorgia.ditano2@unibo.it.
Alessandro GodonoDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy . alessandro.godono@unito.it.
Paola RosselloDepartment of Public Health Sciences, University of Turin, Turin, Italy.. prossello@cittadellasalute.to.it.
Maurizio CoggiolaDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy . maurizio.coggiola54@gmail.com.
Enrico PiraDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.. enrico.pira@unito.it.
Paolo BoffettaDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy; Stony Brook Cancer Center, Stony Brook University, Stony Brook, New York, USA. paolo.boffetta@unibo.it.
Working Group On Sars-Cov-PreventionDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy . Sarscov2prevention@unito.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate the association between personal protective equipment (PPE) use and SARS-CoV-2 infection among healthcare workers (HCWs).

methodsWe analyzed occupational surveillance contact forms followed by a PCR test notified between March and September 2020 by Italian HCWs. The odds ratios (ORs) and 95% Confidence Intervals (CIs) for positive PCR based on HCWs and contacts characteristics were calculated through multivariable logistic regression models. When multiple contacts were potentially effective for a PCR test, they were weighted by the inverse of their number.

resultsOverall, 4,883 contacts reported by 2,952 HCWs were analyzed, and 224 contacts among 144 HCWs had positive PCR. No difference was found according to sex, age, employment, or job title, except for an OR of 0.30 (95%CI 0.11-0.78) for resident physicians, compared to administrative staff. The ORs for use of surgical mask were 0.59 (95%CI=0.40-0.86) for use only by HCW, 0.49 (95%CI=0.22-1.07) only by the infected person, and 0.40 (95%CI=0.27-0.60) by both, compared to use by neither. Use of other PPEs was not associated with infection, while the OR for hand sanitation was 0.61 (95%CI=0.40-0.93). HCWs reporting fever, cough, and asthenia had a higher risk of infection.

conclusionsUse of surgical masks was associated with a 40-60% lower risk of infection, especially when both HCWs and infected individuals used them. Our results quantify the role played by mask use and hand sanitation in preventing SARS-CoV-2 transmission in high-risk circumstances.

Indexed as

COVID-19SARS-CoV-2Health PersonnelHumans

Identifiers

PMID36475504
PMCPMC9766841

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.