Evidence map›Paper›PMID 36475502›Full record

ArticleLa Medicina del lavoro2022

The role of chance in cancer causation.

Marco Angelini, Giulia Collatuzzo, Federica Teglia, Michele Sassano, Andrei Cosmin Siea, Paolo Boffetta

Abstract read
In one paragraph

Article in La Medicina del lavoro, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco AngeliniDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. marco.angelini17@studio.unibo.it.
Giulia CollatuzzoDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. giulia.collatuzzo@studio.unibo.it.
Federica TegliaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. federica.teglia@studio.unibo.it.
Michele SassanoDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. michele.sassano3@unibo.it.
Andrei Cosmin SieaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. andreicosmin.siea@studio.unibo.it.
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, New York NY, USA. paolo.boffetta@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last years, the discussion about the role of chance in the causation of cancer has generated much scientific and public debate. The concept that chance, or "bad luck", as responsible for a majority of the variation of cancer incidence, may be misleading, possibly causing an underestimation of the role played by known risk factors. In this commentary we discuss how host and external factors interact with chance in cancer causation in different ways, and provide examples of situations where chance appears to play only a minor role on cancer onset.

Indexed as

NeoplasmsHumans

Identifiers

PMID36475502
PMCPMC9766839

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.