Evidence map›Paper›PMID 36475439›Full record

ArticleProceedings. Biological sciences2022

Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation.

Daniel Divín, Mercedes Goméz Samblas, Nithya Kuttiyarthu Veetil, Eleni Voukali, Zuzana Świderská, Tereza Krajzingrová, Martin Těšický, Vladimír Beneš, Daniel Elleder, Oldřich Bartoš and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Daniel DivínFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.ORCID 0000-0001-8513-7214
Mercedes Goméz SamblasFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.
Nithya Kuttiyarthu VeetilFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.ORCID 0000-0002-1202-4902
Eleni VoukaliFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.
Zuzana ŚwiderskáFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.
Tereza KrajzingrováFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.
Martin TěšickýFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.
Vladimír BenešGenomics Core Facility, European Molecular Biology Laboratory Heidelberg, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Daniel EllederInstitute of Molecular Genetics, Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Oldřich BartošMilitary Health Institute, Military Medical Agency, Tychonova 1, 160 01 Prague 6, Czech Republic.
Michal VinklerFaculty of Science, Department of Zoology, Charles University, Viničná 7, Prague 128 44, Czech Republic.ORCID 0000-0003-3572-9494
Charles University · CZCzech Academy of Sciences · CZEuropean Molecular Biology Laboratory · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vertebrates, cannabinoids modulate neuroimmune interactions through two cannabinoid receptors (CNRs) conservatively expressed in the brain (CNR1, syn. CB1) and in the periphery (CNR2, syn. CB2). Our comparative genomic analysis indicates several evolutionary losses in the

Indexed as

ParrotsAnimalsReceptors, CannabinoidReceptors, Cannabinoidavian immunologycannabinoid receptor pseudogenizationcannabinoid receptorsgene lossneural inflammationneuroimmunology

Identifiers

PMID36475439
PMCPMC9727682
OpenAlexW4311580580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.